The bacterial quorum sensing molecule N-(3-oxo-acyl)homoserine lactone inhibits tumor growth independent of Bcl-2 proteins

被引：0
|
作者：
Neely, Aaron M. [1 ,2 ]
Zhao, Guoping [1 ,2 ]
Schwarzer, Christian [5 ]
Lu, Huayi [6 ]
Whitt, Aaron G. [1 ,2 ]
Stivers, Nicole S. [1 ,2 ]
Burlison, Joseph A. [3 ,4 ]
Machen, Terry [5 ]
Li, Chi [1 ,2 ]
机构：
[1] Univ Louisville, Dept Pharmacol, Mol Targets Program, Louisville, KY 40292 USA
[2] Univ Louisville, Dept Toxicol, Louisville, KY 40292 USA
[3] Univ Louisville, James Graham Brown Canc Ctr, Dept Pharmacol, Struct Biol Program, Louisville, KY 40292 USA
[4] Univ Louisville, James Graham Brown Canc Ctr, Dept Toxicol, Med, Louisville, KY 40292 USA
[5] Univ Calif Berkeley, Dept Mol & Cell Biol, 229 Stanley Hall, Berkeley, CA 94720 USA
[6] Jilin Univ, Hosp 2, Changchun, Jilin, Peoples R China
来源：
FASEB JOURNAL | 2017年 / 31卷
基金：
美国国家卫生研究院;
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
823.1
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone
    Shiyu Tao
    Yanwen Luo
    Jie Bin He
    Xi Liu
    Yingdong Qian
    Ruqian Ni
    Scientific Reports, 6
  • [42] N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans
    Bin Chen
    Xianbin Cao
    Huayi Lu
    Pengbo Wen
    Xiaojing Qi
    Shaopeng Chen
    Lijun Wu
    Chi Li
    An Xu
    Guoping Zhao
    Apoptosis, 2018, 23 : 626 - 640
  • [43] Ochrobactrum sp Pv2Z2 exhibits multiple traits of plant growth promotion, biodegradation and N-acyl-homoserine-lactone quorum sensing
    Imran, Asma
    Saadalla, Marryam Jumma Abdulla
    Khan, Sami-Ullah
    Mirza, Muhammad Sajjad
    Malik, Kauser Abdulla
    Hafeez, Fauzia Yusuf
    ANNALS OF MICROBIOLOGY, 2014, 64 (04) : 1797 - 1806
  • [44] The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone
    Kaufmann, Gunnar F.
    Park, Junguk
    Mee, Jenny M.
    Ulevitch, Richard J.
    Janda, Kim D.
    MOLECULAR IMMUNOLOGY, 2008, 45 (09) : 2710 - 2714
  • [45] Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone inhibits expression of P2Y receptors in cystic fibrosis tracheal gland cells
    Saleh, A
    Figarella, C
    Kammouni, W
    Marchand-Pinatel, S
    Lazdunski, A
    Tubul, A
    Brun, P
    Merten, MD
    INFECTION AND IMMUNITY, 1999, 67 (10) : 5076 - 5082
  • [46] Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl) homoserine lactone attenuates lipopolysaccharide-induced inflammation by activating the unfolded protein response
    Zhang, Jiangguo
    Gong, Fengyun
    Li, Ling
    Zhao, Manzhi
    Song, Jianxin
    BIOMEDICAL REPORTS, 2014, 2 (02) : 233 - 238
  • [47] Effects of N-(3 oxododecanoyl)-L homoserine lactone, a quorum sensing signal molecule belonging to Pseudomonas aeruginosa, over human pancreas cell (hTERT-HPNE)
    Yavuz, C.
    Yildirim, T.
    Sivas, H.
    FEBS OPEN BIO, 2018, 8 : 97 - 97
  • [48] Pseudomonas aeruginosa Quorum Sensing Molecule N-(3-Oxododecanoyl)-L-Homoserine-Lactone Induces HLA-G Expression in Human Immune Cells
    Bortolotti, Daria
    LeMaoult, Joel
    Trapella, Claudio
    Di Luca, Dario
    Carosella, Edgardo D.
    Rizzo, Roberta
    INFECTION AND IMMUNITY, 2015, 83 (10) : 3918 - 3925
  • [49] N-(3-oxo-hexanoyl)-homoserine lactone has a critical contribution to the quorum-sensing-dependent regulation in phytopathogen Pseudomonas syringae pv. tabaci 11528
    Cheng, Feifei
    Ma, Anzhou
    Zhuang, Xuliang
    He, Xiaojia
    Zhuang, Guoqiang
    FEMS MICROBIOLOGY LETTERS, 2016, 363 (23)
  • [50] Ochrobactrum sp. Pv2Z2 exhibits multiple traits of plant growth promotion, biodegradation and N-acyl-homoserine-lactone quorum sensing
    Asma Imran
    Marryam Jumma Abdulla Saadalla
    Sami-Ullah Khan
    Muhammad Sajjad Mirza
    Kauser Abdulla Malik
    Fauzia Yusuf Hafeez
    Annals of Microbiology, 2014, 64 : 1797 - 1806
12345