Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

被引:332
|
作者
Grady, WM
Willis, J
Guilford, PJ
Dunbier, AK
Toro, TT
Lynch, H
Wiesner, G
Ferguson, K
Eng, C
Park, JG
Kim, SJ
Markowitz, S [1 ]
机构
[1] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Sch Med, Dept Pathol, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ, Sch Med, Dept Human Genet, Cleveland, OH 44106 USA
[4] Case Western Reserve Univ, Sch Med, Ireland Canc Ctr, Cleveland, OH 44106 USA
[5] Univ Hosp Cleveland, Cleveland, OH 44106 USA
[6] Univ Otago, Dept Biochem, Canc Genet Lab, Dunedin, New Zealand
[7] Creighton Univ, Sch Med, Dept Prevent Med, Omaha, NE 68178 USA
[8] Ohio State Univ, Sch Med, Clin Canc Genet Program, Ctr Comprehens Canc, Columbus, OH 43210 USA
[9] Ohio State Univ, Sch Med, Human Canc Genet Program, Ctr Comprehens Canc, Columbus, OH 43210 USA
[10] Ohio State Univ, Sch Med, Div Human Genet, Dept Internal Med, Columbus, OH 43210 USA
[11] Seoul Natl Univ Hosp, Dept Surg, Seoul 110744, South Korea
[12] NCI, Lab Cell Regulat & Carcinogenesis, NIH, Bethesda, MD 20892 USA
[13] Howard Hughes Med Inst, Cleveland, OH USA
关键词
D O I
10.1038/79120
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:16 / 17
页数:2
相关论文
共 50 条
  • [41] EARLY GENETIC COUNSELING AND DETECTION OF CDH1 MUTATION IN ASYMPTOMATIC CARRIERS IMPROVES SURVIVAL IN HEREDITARY DIFFUSE GASTRIC CANCER
    Moslim, Maitham A.
    Heald, Brandie
    Burke, Carol A.
    Walsh, R. Matthew
    GASTROENTEROLOGY, 2018, 154 (06) : S1259 - S1260
  • [42] Hereditary diffuse gastric cancer in a Japanese family with CDH1 mutation three case reports
    Muranaka, Futoshi
    Kise, Emiko
    Tokumaru, Shigeo
    Kitazawa, Masato
    Miyagawa, Yusuke
    Suga, Tomoaki
    Uehara, Takeshi
    Iwaya, Mai
    Kobayashi, Shota
    Sato, Midori
    Gomi, Daisuke
    Yamada, Hidetaka
    Sugimura, Haruhiko
    Kosho, Tomoki
    Soejima, Yuji
    Koizumi, Tomonobu
    DISCOVER ONCOLOGY, 2023, 14 (01)
  • [43] Cleft lip, cleft palate, hereditary diffuse gastric cancer and germline mutations in CDH1
    Benusiglio, Patrick R.
    Caron, Olivier
    Consolino, Emilie
    Duvillard, Pierre
    Coulet, Florence
    Blayau, Martine
    Malka, David
    INTERNATIONAL JOURNAL OF CANCER, 2013, 132 (10) : 2470 - 2470
  • [44] Breast Cancer Events Associated with Germline Mutations of the CDH1 Gene (Hereditary Diffuse Gastric Cancer)
    Hebbart, P. C.
    MacMillan, A.
    McCarthy, J.
    Laing, K.
    Wadden, N.
    Green, J.
    Fernandez, B.
    Kwan, A.
    Wirtzfeld, D. A.
    CANCER RESEARCH, 2009, 69 (24) : 532S - 532S
  • [45] Hereditary diffuse gastric cancer in a Japanese family with CDH1 mutation three case reports
    Futoshi Muranaka
    Emiko Kise
    Shigeo Tokumaru
    Masato Kitazawa
    Yusuke Miyagawa
    Tomoaki Suga
    Takeshi Uehara
    Mai Iwaya
    Shota Kobayashi
    Midori Sato
    Daisuke Gomi
    Hidetaka Yamada
    Haruhiko Sugimura
    Tomoki Kosho
    Yuji Soejima
    Tomonobu Koizumi
    Discover Oncology, 14
  • [46] Germline CDH1 variants in hereditary diffuse gastric cancer syndrome with focus on younger women
    Corso, Giovanni
    Comelli, Giovanni
    Veronesi, Paolo
    Bianchi, Beatrice
    Petitto, Salvatore
    Polizzi, Andrea
    Girardi, Antonia
    Cioffi, Antonio
    La Vecchia, Carlo
    Bagnardi, Vincenzo
    Magnoni, Francesca
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (17) : 16147 - 16155
  • [47] Hereditary diffuse gastric cancer due to a previously undescribed CDH1 splice site mutation
    Matsukuma, Karen E.
    Mullins, Franklin M.
    Dietz, Lisa
    Zehnder, James L.
    Ford, James M.
    Chun, Nicolette M.
    Schrijver, Iris
    HUMAN PATHOLOGY, 2010, 41 (08) : 1200 - 1203
  • [48] Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer
    Tedaldi, Gianluca
    Molinari, Chiara
    Jose, Celina Sao
    Barbosa-Matos, Rita
    Andre, Ana
    Danesi, Rita
    Arcangeli, Valentina
    Ravegnani, Mila
    Saragoni, Luca
    Morgagni, Paolo
    Rebuzzi, Francesca
    Canale, Matteo
    Pignatta, Sara
    Ferracci, Elisa
    Martinelli, Giovanni
    Ranzani, Guglielmina Nadia
    Oliveira, Carla
    Calistri, Daniele
    Ulivi, Paola
    PHARMACEUTICALS, 2021, 14 (05)
  • [49] Clinical implication of CDH1 mutations in genetic testing for diffuse gastric cancer patients
    Corso, Giovanni
    Trovato, Cristina Maria
    Petitto, Salvatore
    Girardi, Antonia
    De Scalzi, Alessandra Margherita
    Bianchi, Beatrice
    Magnoni, Francesca
    Cioffi, Antonio
    Galimberti, Viviana
    Veronesi, Paolo
    Mazzarol, Giovanni
    Maisonneuve, Patrick
    ONCOLOGY, 2024, 102 (04) : 374 - 379
  • [50] CDH1 Analysis in Familial Diffuse Gastric Cancer in Korea
    Chung, Jun-Won
    Lee, Woo Chang
    Kim, Yoon Jae
    Jung, Hwoon-Yong
    Hahm, Ki-Baik
    DIGESTION, 2011, 83 (03) : 230 - 230