Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

被引：332
|
作者：
Grady, WM
Willis, J
Guilford, PJ
Dunbier, AK
Toro, TT
Lynch, H
Wiesner, G
Ferguson, K
Eng, C
Park, JG
Kim, SJ
Markowitz, S [1 ]
机构：
[1] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Sch Med, Dept Pathol, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ, Sch Med, Dept Human Genet, Cleveland, OH 44106 USA
[4] Case Western Reserve Univ, Sch Med, Ireland Canc Ctr, Cleveland, OH 44106 USA
[5] Univ Hosp Cleveland, Cleveland, OH 44106 USA
[6] Univ Otago, Dept Biochem, Canc Genet Lab, Dunedin, New Zealand
[7] Creighton Univ, Sch Med, Dept Prevent Med, Omaha, NE 68178 USA
[8] Ohio State Univ, Sch Med, Clin Canc Genet Program, Ctr Comprehens Canc, Columbus, OH 43210 USA
[9] Ohio State Univ, Sch Med, Human Canc Genet Program, Ctr Comprehens Canc, Columbus, OH 43210 USA
[10] Ohio State Univ, Sch Med, Div Human Genet, Dept Internal Med, Columbus, OH 43210 USA
[11] Seoul Natl Univ Hosp, Dept Surg, Seoul 110744, South Korea
[12] NCI, Lab Cell Regulat & Carcinogenesis, NIH, Bethesda, MD 20892 USA
[13] Howard Hughes Med Inst, Cleveland, OH USA
来源：
NATURE GENETICS | 2000年 / 26卷 / 01期
关键词：
D O I：
10.1038/79120
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：16 / 17
页数：2
相关论文
共 50 条
  • [31] Totally Unexpected: Nonsyndromic CDH1 Mutations and Hereditary Diffuse Gastric Cancer Syndrome
    Ford, James M.
    JCO PRECISION ONCOLOGY, 2017, 1
  • [32] Computational analysis of cdh1 missense mutations in the cause of hereditary diffuse gastric cancer
    Santhiya, S.
    Shanthi, V.
    Rajasekaran, R.
    Ramanathan, Karuppasamy
    BANGLADESH JOURNAL OF PHARMACOLOGY, 2013, 8 (02) : 207 - 213
  • [33] New Variants in the CDH1 Gene in Iranian Families with Hereditary Diffuse Gastric Cancer
    Kheirollahi, Majid
    Saneipour, Maryam
    Tabatabaiefar, Mohammad Amin
    Zeinalian, Mehrdad
    Minakari, Mohammad
    Moridnia, Abbas
    MIDDLE EAST JOURNAL OF CANCER, 2020, 11 (04) : 493 - 501
  • [34] Predicting the Functional Impact of CDH1 Missense Mutations in Hereditary Diffuse Gastric Cancer
    Melo, Soraia
    Figueiredo, Joana
    Fernandes, Maria Sofia
    Goncalves, Margarida
    Morais-de-Sa, Eurico
    Sanches, Joao Miguel
    Seruca, Raquel
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (12)
  • [35] Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice
    Guilford, Parry
    Humar, Bostjan
    Blair, Vanessa
    GASTRIC CANCER, 2010, 13 (01) : 1 - 10
  • [36] Early genetic counseling and detection of CDH1 mutation in asymptomatic carriers improves survival in hereditary diffuse gastric cancer
    Moslim, Maitham A.
    Heald, Brandie
    Tu, Chao
    Burke, Carol A.
    Walsh, R. Matthew
    SURGERY, 2018, 164 (04) : 754 - 759
  • [37] FACTORS ASSOCIATED WITH THE DETECTION OF HEREDITARY DIFFUSE GASTRIC CANCER ON ENDOSCOPY IN INDIVIDUALS WITH MUTATIONS IN CDH1
    Laszkowska, Monika
    Vos, Elvira L.
    Tang, Laura H.
    Abate, Miseker
    Schattner, Mark A.
    Stadler, Zsofia
    Coit, Daniel
    Strong, Vivian E.
    Markowitz, Arnold J.
    GASTROENTEROLOGY, 2022, 162 (07) : S138 - S138
  • [38] Germline CDH1 variants in hereditary diffuse gastric cancer syndrome with focus on younger women
    Giovanni Corso
    Giovanni Comelli
    Paolo Veronesi
    Beatrice Bianchi
    Salvatore Petitto
    Andrea Polizzi
    Antonia Girardi
    Antonio Cioffi
    Carlo La Vecchia
    Vincenzo Bagnardi
    Francesca Magnoni
    Journal of Cancer Research and Clinical Oncology, 2023, 149 : 16147 - 16155
  • [39] Evaluating the performance of clinicopathological criteria to predict CDH1 mutations in hereditary diffuse gastric cancer
    van der Post, C.
    Manders, P.
    Vogelaar, I.
    Wes, J.
    van der Kolk, L.
    Cats, A.
    Ponz, O. Balague
    Mensenkamp, A.
    Hoogerbrugge, N.
    Ligtenberg, M.
    van Krieken, H.
    VIRCHOWS ARCHIV, 2014, 465 : S23 - S23
  • [40] Laparoscopic Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer in CDH1 Mutation Carriers
    Ithurralde-Argerich, Javier
    Rosner, Laura
    Rizzolo, Mariana
    Faerberg, Alejandro
    Puma, Rolando
    Ferro, Diego
    Duque, Camilo
    Kujaruk, Mirta
    Cuenca-Abente, Federico
    JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, 2021, 31 (07): : 729 - 737
12345