Total synthesis of microcarpalide

被引:46
|
作者
Gurjar, MK [1 ]
Nagaprasad, R [1 ]
Ramana, CV [1 ]
机构
[1] Natl Chem Lab, Pune 411008, Maharashtra, India
关键词
D O I
10.1016/S0040-4039(03)00441-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A total synthesis of the natural product microcarpalide is described. Ring-closing metathesis of a dienic ester was used as the key step. Mannose was used as the chiral pool material for the construction of the olefinic-acid and a Sharpless asymmetric dihydroxylation reaction provided the chiral precursor for the synthesis of the olefinic-alcohol. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2873 / 2875
页数:3
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