Screening strategies for iron chelators in serum free media

被引：0
|
作者：
Keenan, Joanne [1 ]
Pearson, Dermot [2 ]
Clynes, Martin [1 ]
机构：
[1] Dublin City Univ, Natl Inst Cellular Biotechnol, Dublin, Ireland
[2] Delta Biotechnol Ltd, Nottingham, England
来源：
CELL TECHNOLOGY FOR CELL PRODUCTS | 2007年
关键词：
transferrin; iron chelators; recombinant human transferrin; SFM; mammalian cell culture;
D O I：
10.1007/978-1-4020-5476-1_144
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A variety of iron chelators, including recombinant human transferrin, were evaluated as replacements to holo human transferrin on a number of industrially relevant cell lines (MDCK, BHK-21 and Vero). The results showed that short term screening over one passage is not necessarily adequate to select a suitable transferrin replacement.
引用
收藏
页码：785 / +
页数：2
相关论文
共 50 条
  • [31] Antimalarial effect of iron chelators
    Gordeuk, VR
    Loyevsky, M
    IRON CHELATION THERAPY, 2002, 509 : 251 - 272
  • [32] Update on Iron Chelators in Thalassemia
    Neufeld, Ellis J.
    HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM, 2010, : 451 - 455
  • [33] Iron chelators for clinical use
    Tilbrook, GS
    Hider, RC
    METAL IONS IN BIOLOGICAL SYSTEMS, VOL 35: IRON TRANSPORT AND STORAGE IN MICROORGANISMS, PLANTS, AND ANIMALS, 1998, 35 : 691 - 730
  • [34] Iron chelators in cancer chemotherapy
    Buss, JL
    Greene, BT
    Turner, J
    Torti, FM
    Torti, SV
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2004, 4 (15) : 1623 - 1635
  • [35] THE ROLE OF IRON AND IRON CHELATORS IN ANTHRACYCLINE CARDIOTOXICITY
    HERSHKO, C
    LINK, G
    TZAHOR, M
    PINSON, A
    LEUKEMIA & LYMPHOMA, 1993, 11 (3-4) : 207 - 214
  • [36] SERUM-FREE MEDIA MARKETS
    RATAFIA, M
    BIO-TECHNOLOGY, 1989, 7 (06): : 574 - 575
  • [37] Thalassemia: Cardiac Iron and Chelators
    Gaur, Ajay
    INDIAN PEDIATRICS, 2012, 49 (04) : 268 - 269
  • [38] Role of Iron Chelators in Mucormycosis
    Mahalmani, Vidya
    Sarma, Phulen
    Prakash, Ajay
    Medhi, Bikash
    INDIAN JOURNAL OF PHARMACOLOGY, 2021, 53 (04) : 261 - 263
  • [39] Therapeutic Macromolecular Iron Chelators
    Bulbake, Upendra
    Singh, Alka
    Domb, Abraham J.
    Khan, Wahid
    CURRENT MEDICINAL CHEMISTRY, 2019, 26 (02) : 323 - 334
  • [40] Orally active iron chelators
    Merson, L
    Olivieri, N
    BLOOD REVIEWS, 2002, 16 (02) : 127 - 134
12345