Screening strategies for iron chelators in serum free media

被引：0
|
作者：
Keenan, Joanne [1 ]
Pearson, Dermot [2 ]
Clynes, Martin [1 ]
机构：
[1] Dublin City Univ, Natl Inst Cellular Biotechnol, Dublin, Ireland
[2] Delta Biotechnol Ltd, Nottingham, England
来源：
CELL TECHNOLOGY FOR CELL PRODUCTS | 2007年
关键词：
transferrin; iron chelators; recombinant human transferrin; SFM; mammalian cell culture;
D O I：
10.1007/978-1-4020-5476-1_144
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A variety of iron chelators, including recombinant human transferrin, were evaluated as replacements to holo human transferrin on a number of industrially relevant cell lines (MDCK, BHK-21 and Vero). The results showed that short term screening over one passage is not necessarily adequate to select a suitable transferrin replacement.
引用
收藏
页码：785 / +
页数：2
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