Cyclic Voltammetric Studies of Biologically Active Azomethine 2′-Hydroxyacetophenone Sulfamethoxazole

被引：3

作者：

Kumawat, Gopal Lal ^{[1
]}

Choudhary, Preeti ^{[1
]}

Varshney, Anil Kumar ^{[1
]}

Varshney, Sarita ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

ORIENTAL JOURNAL OF CHEMISTRY | 2019年 / 35卷 / 03期

关键词：

2 '-Hydroxyacetophenone sulfamethoxazole; Cyclic voltammetry; Biological activity; SCHIFF-BASE COMPLEXES; ELECTROCHEMICAL-BEHAVIOR; MILD-STEEL; METAL-IONS; CORROSION; ACID; CONDENSATION; INHIBITION; ALDEHYDES; CATALYST;

D O I：

10.13005/ojc/350327

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cyclic voltammetric behavior of newly synthesized biologically active azomethine 2'-hydroxyacetophenone sulfamethoxazole (2'-HyAcPhSM) was examined at glassy carbon electrode in acetonitrile, acetone, methanol and DMF solvents using phosphate buffer and Britton-Robinson (BR) buffer. The effect of solvents, buffers, sweep rates and pH were calculated on peak potential and peak current. The cyclic voltammograms of 2'-HyAcPhSM exhibited two electronic, irreversible and diffusion-controlled single cathodic peak within the entire pH range which is attributed to the reduction of the azomethine group (-CH=N-) to amine group (-CH2-NH-). The biological activity of synthesized 2'-HyAcPhSM compound were carried out against various bacteria and fungi.

引用

页码：1117 / 1124

页数：8

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