Cytokinesis: relative alignment of the cell division apparatus and the mitotic spindle

被引：15
|
作者：
Wang, H [1 ]
Oliferenko, S [1 ]
Balasubramanian, MK [1 ]
机构：
[1] Natl Univ Singapore, Temasek Life Sci Lab, Singapore 117604, Singapore
来源：
CURRENT OPINION IN CELL BIOLOGY | 2003年 / 15卷 / 01期
关键词：
D O I：
10.1016/S0955-0674(02)00006-6
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The cell division apparatus is assembled at different stages of the cell cycle in different eukaryotic organisms. Mechanisms exist in all organisms, however, to ensure that the cell division apparatus and the mitotic spindle are aligned perpendicular to each other. Such an alignment ensures that each daughter cell receives a nucleus and that the cell division apparatus does not cleave and destroy the genetic material. The interaction(s) of astral microtubules with the cell cortex appears to play an important role in establishing perpendicularity between chromosome segregation and cell division machinery.
引用
收藏
页码：82 / 87
页数：6
相关论文
共 50 条
  • [41] ORGANIZATION OF THE MITOTIC APPARATUS DURING GENERATIVE CELL-DIVISION IN NICOTIANA-TABACUM
    PALEVITZ, BA
    PROTOPLASMA, 1993, 174 (1-2) : 25 - 35
  • [42] Cell division: The place and time of cytokinesis
    Gonzalez, C
    CURRENT BIOLOGY, 2003, 13 (09) : R363 - R365
  • [43] ANTIBODY TO THE MITOTIC SPINDLE APPARATUS - IMMUNOLOGICAL CHARACTERISTICS AND CYTOLOGIC STUDIES
    MCCARTY, GA
    VALENCIA, DW
    FRITZLER, MJ
    JOURNAL OF RHEUMATOLOGY, 1984, 11 (02) : 213 - 218
  • [44] AUTOANTIBODIES TO THE MITOTIC SPINDLE APPARATUS IN MYCOPLASMA-PNEUMONIAE DISEASE
    LIND, K
    HOIERMADSEN, M
    WIIK, A
    INFECTION AND IMMUNITY, 1988, 56 (03) : 714 - 715
  • [45] Relative contributions of chromatin and kinetochores to mitotic spindle assembly
    O'Connell, Christopher B.
    Loncarek, Jadranka
    Kalab, Petr
    Khodjakov, Alexey
    JOURNAL OF CELL BIOLOGY, 2009, 187 (01): : 43 - 51
  • [46] SPINDLE BIREFRINGENCE OF ISOLATED MITOTIC APPARATUS ANALYZED BY PRESSURE TREATMENT
    FORER, A
    ZIMMERMAN, AM
    JOURNAL OF CELL SCIENCE, 1976, 20 (02) : 309 - 327
  • [47] Spindle assembly defects leading to the formation of a monopolar mitotic apparatus
    Tillement, Vanessa
    Remy, Marie-Helene
    Raynaud-Messina, Brigitte
    Mazzolini, Laurent
    Haren, Laurence
    Merdes, Andreas
    BIOLOGY OF THE CELL, 2009, 101 (01) : 1 - 11
  • [48] Cell division - New wrinkles in cytokinesis
    Theriot, JA
    Satterwhite, LL
    NATURE, 1997, 385 (6615) : 388 - 389
  • [49] Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
    Farrell, K. C.
    Wang, Jennifer T.
    Stearns, Tim
    ELIFE, 2024, 12
  • [50] Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system
    Julia A. Kaltschmidt
    Catherine M. Davidson
    Nicholas H. Brown
    Andrea H. Brand
    Nature Cell Biology, 2000, 2 : 7 - 12
12345