Cytokinesis: relative alignment of the cell division apparatus and the mitotic spindle

被引：15
|
作者：
Wang, H [1 ]
Oliferenko, S [1 ]
Balasubramanian, MK [1 ]
机构：
[1] Natl Univ Singapore, Temasek Life Sci Lab, Singapore 117604, Singapore
来源：
CURRENT OPINION IN CELL BIOLOGY | 2003年 / 15卷 / 01期
关键词：
D O I：
10.1016/S0955-0674(02)00006-6
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The cell division apparatus is assembled at different stages of the cell cycle in different eukaryotic organisms. Mechanisms exist in all organisms, however, to ensure that the cell division apparatus and the mitotic spindle are aligned perpendicular to each other. Such an alignment ensures that each daughter cell receives a nucleus and that the cell division apparatus does not cleave and destroy the genetic material. The interaction(s) of astral microtubules with the cell cortex appears to play an important role in establishing perpendicularity between chromosome segregation and cell division machinery.
引用
收藏
页码：82 / 87
页数：6
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