Synthesis of Multisubstituted Guanidines through Palladium-Catalyzed Insertion of Isonitriles

被引：5
|
作者：
Li, Pei-Xia [1 ]
Meng, Xiu-Jin [1 ]
Yang, Li [2 ]
Tang, Hai-Tao [1 ]
Pan, Ying-Ming [1 ]
机构：
[1] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, State Key Lab Chem & Mol Engn Med Resources, Guilin 541004, Peoples R China
[2] Guangxi Zhuang Autonomous Region Forestry Res Ins, Guangxi Key Lab Special Nonwood Forest Cultivat &, Nanning 530002, Peoples R China
来源：
SYNLETT | 2018年 / 29卷 / 17期
关键词：
insertion of isonitriles; unactivated amides; cascade transformation; palladium; ISOCYANIDE INSERTION; ANALOGS;
D O I：
10.1055/s-0037-1610981
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new method for the synthesis of multisubstituted guanidines through tandem intermolecular insertion of isonitriles with unactivated amides has been developed. In this study, isonitriles could be used not only as reaction materials but also as the source of amines.
引用
收藏
页码：2326 / 2330
页数：5
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