Stereoselective and regioselective synthesis of N-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates

被引：3

作者：

Ozenc, Aysen Koseceli ^{[1
]}

Celik, Ilhami ^{[1
]}

Kokten, Sule ^{[1
]}

机构：

[1] Anadolu Univ, Fac Sci, Dept Chem, Eskisehir, Turkey

来源：

TURKISH JOURNAL OF CHEMISTRY | 2017年 / 41卷 / 03期

关键词：

Imidazole; benzimidazole; benzotriazole; Baylis Hillman acetates; N-substituted azole acrylates; ADDUCTS; FACILE; ACID; N-(2-AMINOBENZOYL)BENZOTRIAZOLE; ESTERIFICATION; BENZOTRIAZOLE; DERIVATIVES; IMIDAZOLES;

D O I：

10.3906/kim-1607-35

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis-Hillman acetates and a suitable acylazole in the presence of K2CO3 as a base catalyst. The targeted N-substituted azole acrylates were efficiently obtained in good yields (39%-89%).

引用

页码：323 / 334

页数：12

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