Stereoselective and regioselective synthesis of N-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates

被引：3
|
作者：
Ozenc, Aysen Koseceli [1 ]
Celik, Ilhami [1 ]
Kokten, Sule [1 ]
机构：
[1] Anadolu Univ, Fac Sci, Dept Chem, Eskisehir, Turkey
来源：
TURKISH JOURNAL OF CHEMISTRY | 2017年 / 41卷 / 03期
关键词：
Imidazole; benzimidazole; benzotriazole; Baylis Hillman acetates; N-substituted azole acrylates; ADDUCTS; FACILE; ACID; N-(2-AMINOBENZOYL)BENZOTRIAZOLE; ESTERIFICATION; BENZOTRIAZOLE; DERIVATIVES; IMIDAZOLES;
D O I：
10.3906/kim-1607-35
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
N-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis-Hillman acetates and a suitable acylazole in the presence of K2CO3 as a base catalyst. The targeted N-substituted azole acrylates were efficiently obtained in good yields (39%-89%).
引用
收藏
页码：323 / 334
页数：12
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