Iron-catalyzed indolo[2,3-c]quinoline synthesis from nitroarenes and benzylic alcohols/aldehydes promoted by elemental sulfur

被引：26
|
作者：
Li, Rong [1 ]
Jiang, Shuxin [1 ]
Zheng, Haolin [1 ]
Lei, Hanwen [1 ]
Chen, Shanping [1 ]
Deng, Guo-Jun [1 ,2 ]
机构：
[1] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat,Minist E, Xiangtan 411105, Peoples R China
[2] South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregates, Guangzhou 510640, Peoples R China
来源：
GREEN SYNTHESIS AND CATALYSIS | 2022年 / 3卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Iron-catalyzed; Nitro reduction; Alcohol oxidation; Oxidative annulation; Indolo[2; c ]quinolines; HYDROGENATION; IMINES;
D O I：
10.1016/j.gresc.2021.11.006
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed. This cascade reaction involving alcohol oxidation, nitro reduction, and oxidative annulation was achieved in a one-pot. The present protocol was started from mono-functionalized indoles and readily available benzylic alcohols/aldehydes, affording a variety of functionalized indolo[2,3-c]quinolines in satisfactory yields.
引用
收藏
页码：95 / 101
页数：7
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