Iron-catalyzed indolo[2,3-c]quinoline synthesis from nitroarenes and benzylic alcohols/aldehydes promoted by elemental sulfur

被引：26

作者：

Li, Rong ^{[1
]}

Jiang, Shuxin ^{[1
]}

Zheng, Haolin ^{[1
]}

Lei, Hanwen ^{[1
]}

Chen, Shanping ^{[1
]}

Deng, Guo-Jun ^{[1
,2
]}

机构：

[1] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat,Minist E, Xiangtan 411105, Peoples R China

[2] South China Univ Technol, Guangdong Prov Key Lab Luminescence Mol Aggregates, Guangzhou 510640, Peoples R China

来源：

GREEN SYNTHESIS AND CATALYSIS | 2022年 / 3卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Iron-catalyzed; Nitro reduction; Alcohol oxidation; Oxidative annulation; Indolo[2; c ]quinolines; HYDROGENATION; IMINES;

D O I：

10.1016/j.gresc.2021.11.006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed. This cascade reaction involving alcohol oxidation, nitro reduction, and oxidative annulation was achieved in a one-pot. The present protocol was started from mono-functionalized indoles and readily available benzylic alcohols/aldehydes, affording a variety of functionalized indolo[2,3-c]quinolines in satisfactory yields.

引用

页码：95 / 101

页数：7

共 32 条

[31] One-Pot Synthesis of Orange-Red Fluorescent Dimeric 2H-Pyrrolo[2,3-c]isoquinoline-2,5(3H)-diones from Benzamides and Maleimides via Ru(II)-Catalyzed Sequential C-C/C-N/C-C Bond Formation
Jaiswal, Yogesh
Mandal, Saptarshi
Das, Prolay
Kumar, Amit
ORGANIC LETTERS, 2020, 22 (04) : 1605 - 1610
[32] AN ADDUCT BETWEEN CPRH(S2C2Z2) AND ZC=CZ (Z=COOCH3) AS AN INTERMEDIATE IN CPRHI-CATALYZED SYNTHESIS OF TETRAMETHYL-2,3,4,5-THIOPHENETETRACARBOXYLATE FROM ELEMENTAL SULFUR AND ZC=CZ
KAJITANI, M
SUETSUGU, T
WAKABAYASHI, R
IGARASHI, A
AKIYAMA, T
SUGIMORI, A
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1985, 293 (01) : C15 - C18

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