Iron-Catalyzed Synthesis of Substituted Thiazoles from Enamines and Elemental Sulfur through C-S Bond Formation

被引：48
|
作者：
Wu, Mingzhong [1 ]
Jiang, Yong [2 ]
An, Zhenyu [1 ]
Qi, Zhenjie [1 ]
Yan, Rulong [1 ]
机构：
[1] Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou, Gansu, Peoples R China
[2] Yangtze Normal Univ, Sch Chem & Chem Engn, Chongqing, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 21期
基金：
中国国家自然科学基金;
关键词：
Thiazoles; enamines; elemental sulfur; C-S bond; METAL-FREE CONDITIONS; REDOX CONDENSATION REACTION; SULFONYL HYDRAZIDES; HOMOPROPARGYLIC ALCOHOLS; O-HALONITROBENZENES; DIRECT THIOLATION; NATURAL-PRODUCTS; FACILE SYNTHESIS; MILD CONDITIONS; 3-COMPONENT;
D O I：
10.1002/adsc.201800693
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An atom economical approach for the synthesis of substituted thiazoles starting from enamines and elemental sulfur through the C-H functionalization/C-S bond formation is described. Under the optimized conditions, various substituted enamines reacted smoothly with elemental sulfur and the desired substituted thiazoles were generated in moderate to excellent yields.
引用
收藏
页码：4236 / 4240
页数：5
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