Diverse mechanisms of PARP inhibitor resistance in ovarian cancer

被引:18
|
作者
Wakefield, Matthew John [1 ,2 ]
Nesic, Ksenija [1 ,3 ]
Kondrashova, Olga [4 ]
Scott, Clare L. [1 ,2 ]
机构
[1] Walter & Eliza Hall Inst Med Res, Parkville, Vic 3052, Australia
[2] Univ Melbourne, Royal Womens Hosp, Dept Obstet & Gynaecol, Parkville, Vic 3052, Australia
[3] Univ Melbourne, Dept Med Biol, Parkville, Vic 3010, Australia
[4] QIMR Berghofer Med Res Inst, Herston, Qld 4006, Australia
来源
基金
英国医学研究理事会;
关键词
REPLICATION FORK REVERSAL; CELL-FREE DNA; HOMOLOGOUS RECOMBINATION; MRE11-DEPENDENT DEGRADATION; GERMLINE MUTATIONS; EXCISION-REPAIR; MUTANT-CELLS; NASCENT DNA; BRCA2; STABILITY;
D O I
10.1016/j.bbcan.2019.08.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页数:5
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