Potent and selective ligands for adenosine binding sites

被引：8
|
作者：
Cristalli, G
Camaioni, E
DiFrancesco, E
Eleuteri, A
Vittori, S
Volpini, R
机构：
来源：
NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 7-9期
关键词：
D O I：
10.1080/07328319708006189
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A number of selective ligands for the different binding sites of adenosine have been synthesized and tested in several pharmacological models. The aim of these synthetic efforts is both to improve the knowledge of structure-activity relationships in the adenosine-related biological systems and to develop drugs from some of these molecules.
引用
收藏
页码：1379 / 1388
页数：10
相关论文
共 50 条
  • [21] The Role of Selective Adenosine Receptor Ligands on Inflammatory Pain
    Alsalem, Mohammad
    Haddad, Mansour
    FASEB JOURNAL, 2022, 36
  • [22] INTERACTION OF SELECTIVE MU-LIGANDS AND DELTA-LIGANDS WITH THE KAPPA-2 SUBTYPE OF OPIATE BINDING-SITES
    GOUARDERES, C
    ATTALI, B
    AUDIGIER, Y
    CROS, J
    LIFE SCIENCES, 1983, 33 : 175 - 178
  • [23] Synthesis and binding studies of trishomocubanes:: Novel ligands for σ binding sites
    Liu, X
    Kassiou, M
    Christie, MJ
    AUSTRALIAN JOURNAL OF CHEMISTRY, 1999, 52 (07) : 653 - 656
  • [24] CHARACTERIZATION OF A NOVEL CLASS OF POTENT AND SELECTIVE PHENCYCLIDINE LIGANDS
    CONTRERAS, PC
    BREMER, M
    CHENG, B
    GRAY, NM
    FASEB JOURNAL, 1991, 5 (04): : A500 - A500
  • [25] TETRAHYDROPYRIDINE OXIMES AS POTENT SELECTIVE SIGMA-LIGANDS
    PEI, Y
    TECLE, H
    BERGMEIER, S
    MOOS, W
    WISE, L
    COUGHENOUR, L
    PUGSLEY, T
    HEFFNER, T
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 201 : 124 - MEDI
  • [26] Docking small ligands in flexible binding sites
    Apostolakis, J
    Pluckthun, A
    Caflisch, A
    JOURNAL OF COMPUTATIONAL CHEMISTRY, 1998, 19 (01) : 21 - 37
  • [27] BINDING OF SPECIFIC LIGANDS TO ADENOSINE-TRIPHOSPHATE PHOSPHORIBOSYLTRANSFERASE
    DALLLARSEN, T
    KLUNGSOYR, L
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1976, 69 (01): : 195 - 201
  • [28] Identifying protein binding sites and optimal ligands
    Beuscher, A
    Olson, AJ
    Goodsell, DS
    LETTERS IN DRUG DESIGN & DISCOVERY, 2005, 2 (06) : 483 - 489
  • [29] BINDING THERMODYNAMICS OF ADENOSINE A(2A) RECEPTOR LIGANDS
    BOREA, PA
    DALPIAZ, A
    VARANI, K
    GUERRA, L
    GILLI, G
    BIOCHEMICAL PHARMACOLOGY, 1995, 49 (04) : 461 - 469
  • [30] XANTHINE FUNCTIONALIZED CONGENERS AS POTENT LIGANDS AT ADENOSINE-A2 RECEPTORS
    JACOBSON, KA
    UKENA, D
    PADGETT, W
    DALY, JW
    KIRK, KL
    JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (01) : 211 - 214
12345