Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives

被引：60
|
作者：
Glomb, Teresa [1 ]
Swiatek, Piotr [1 ]
机构：
[1] Wroclaw Med Univ, Dept Med Chem, Fac Pharm, Borowska 211, PL-50556 Wroclaw, Poland
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2021年 / 22卷 / 13期
关键词：
1; 3; 4-oxadiazole; antimicrobial activity; antibacterial activity; antifungal activity; antiprotozoal activity; antiviral activity; SILICO MOLECULAR DOCKING; BIOLOGICAL EVALUATION; IN-VITRO; SUBSTITUTED NAPHTHYRIDINES; PHARMACOLOGICAL EVALUATION; CLUBBED 1,3,4-OXADIAZOLES; ANTIBACTERIAL EVALUATION; OXADIAZOLE HYBRIDS; ANALOGS SYNTHESIS; MANNICH-BASES;
D O I：
10.3390/ijms22136979
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The worldwide development of antimicrobial resistance forces scientists to search for new compounds to which microbes would be sensitive. Many new structures contain the 1,3,4-oxadiazole ring, which have shown various antimicrobial activity, e.g., antibacterial, antitubercular, antifungal, antiprotozoal and antiviral. In many publications, the activity of new compounds exceeds the activity of already known antibiotics and other antimicrobial agents, so their potential as new drugs is very promising. The review of active antimicrobial 1,3,4-oxadiazole derivatives is based on the literature from 2015 to 2021.
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页数：23
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