mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France

被引：22
|
作者：
Caspar, Yvan [1 ]
Maillet, Mylene [1 ]
Pavese, Patricia [1 ]
Francony, Gilles [1 ]
Brion, Jean-Paul [1 ]
Mallaret, Marie-Reine [1 ]
Bonnet, Richard [2 ,3 ,4 ,5 ,6 ,7 ]
Robin, Frederic [2 ,3 ,4 ,5 ,6 ,7 ]
Beyrouthy, Racha [2 ,3 ,4 ,5 ,6 ,7 ]
Maurin, Max [1 ]
机构：
[1] Ctr Hosp Univ Grenoble Alpes, Grenoble, France
[2] Univ Grenoble Alpes, CNRS, Grenoble, France
[3] Ctr Hosp Univ Clermont Ferrand, Clermont Ferrand, France
[4] Ctr Natl Reference Resistance Antibiot, Clermont Ferrand, France
[5] Univ Clermont Auvergne, Clermont Ferrand, France
[6] INSERM, Clermont Ferrand, France
[7] INRA, Clermont Ferrand, France
来源：
EMERGING INFECTIOUS DISEASES | 2017年 / 23卷 / 05期
关键词：
REAL-TIME PCR; POLYMYXIN RESISTANCE; PLASMID;
D O I：
10.3201/eid2305.161942
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We report intestinal carriage of an extended-spectrum 13-lactamase producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance.
引用
收藏
页码：874 / 876
页数：3
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