mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France

被引：22

作者：

Caspar, Yvan ^{[1
]}

Maillet, Mylene ^{[1
]}

Pavese, Patricia ^{[1
]}

Francony, Gilles ^{[1
]}

Brion, Jean-Paul ^{[1
]}

Mallaret, Marie-Reine ^{[1
]}

Bonnet, Richard ^{[2
,3
,4
,5
,6
,7
]}

Robin, Frederic ^{[2
,3
,4
,5
,6
,7
]}

Beyrouthy, Racha ^{[2
,3
,4
,5
,6
,7
]}

Maurin, Max ^{[1
]}

机构：

[1] Ctr Hosp Univ Grenoble Alpes, Grenoble, France

[2] Univ Grenoble Alpes, CNRS, Grenoble, France

[3] Ctr Hosp Univ Clermont Ferrand, Clermont Ferrand, France

[4] Ctr Natl Reference Resistance Antibiot, Clermont Ferrand, France

[5] Univ Clermont Auvergne, Clermont Ferrand, France

[6] INSERM, Clermont Ferrand, France

[7] INRA, Clermont Ferrand, France

来源：

EMERGING INFECTIOUS DISEASES | 2017年 / 23卷 / 05期

关键词：

REAL-TIME PCR; POLYMYXIN RESISTANCE; PLASMID;

D O I：

10.3201/eid2305.161942

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report intestinal carriage of an extended-spectrum 13-lactamase producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance.

引用

页码：874 / 876

页数：3

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