Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits

被引：1
|
作者：
Zhou, Feng [1 ]
Butterworth, Adam S. [2 ,3 ,4 ,5 ,6 ]
Asimit, Jennifer L. [1 ]
机构：
[1] Univ Cambridge, MRC Biostat Unit, Cambridge CB2 0SR, England
[2] Univ Cambridge, Dept Publ Hlth & Primary Care, British Heart Fdn, Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England
[3] Univ Cambridge, Natl Inst Hlth Res, Blood & Transplant Res Unit Donor Hlth & Genom, Cambridge CB1 8RN, England
[4] Univ Cambridge, British Heart Fdn, Ctr Res Excellence, Cambridge CB1 8RN, England
[5] Wellcome Genome Campus, Hlth Data Res UK Cambridge, Cambridge CB10 1SA, England
[6] Univ Cambridge, Cambridge CB10 1SA, England
来源：
BIOINFORMATICS | 2022年 / 38卷 / 17期
基金：
英国医学研究理事会;
关键词：
GENOME; HISTORY;
D O I：
10.1093/bioinformatics/btac453
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
flashfm-ivis provides a suite of interactive visualization plots to view potential causal genetic variants that underlie associations that are shared or distinct between multiple quantitative traits and compares results between single- and multi-trait fine-mapping. Unique features include network diagrams that show joint effects between variants for each trait and regional association plots that integrate fine-mapping results, all with user-controlled zoom features for an interactive exploration of potential causal variants across traits.
引用
收藏
页码：4238 / 4242
页数：5
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