A New Lignanamide from the Root of Lycium yunnanense Kuang and Its Antioxidant Activity

被引：18
|
作者：
Zheng, Xin-Heng [1 ]
Huang, Yuan-Peng [1 ]
Liang, Qiu-Ping [1 ]
Xu, Wei [1 ]
Lan, Ting [1 ]
Zhou, Guang-Xiong [1 ]
机构：
[1] Jinan Univ, Coll Pharm, Guangdong Prov Key Lab Pharmacodynam Constituents, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
来源：
MOLECULES | 2018年 / 23卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Lycium yunnanense Kuang; lyciumamide K; ECD calculations; antioxidant activities; oxygen radical absorbance capacity (ORAC) assay; BARK; CHINENSE; GLYCOSIDES; BARBARUM; AMIDES; FRUITS; ASSAY;
D O I：
10.3390/molecules23040770
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new lignanamide (1), lyciumamide K, together with four known analogues (2-5), was isolated from the root of Lycium yunnanense Kuang. Based on HR-ESI-MS, NMR spectral data and quantum chemistry ECD calculations, the structure of this new compound was confirmed, including its absolute configuration. Evaluation of the antioxidant activity of compounds 1-5 in the oxygen radical absorption capacity (ORAC) assay showed that they all exhibited significant antioxidant activities. Particularly, compound 1 showed the best activity with ORAC values (U/mol) of 7.90 +/- 0.52. Thus, the new lignanamide may be a good source of bioavtive and protective compounds.
引用
收藏
页数：8
相关论文
共 50 条
  • [41] A new pseudodepsidone from the Antarctic lichen Stereocaulon alpinum and its antioxidant, antibacterial activity
    Hari Datta Bhattarai
    Taikyung Kim
    Hyuncheol Oh
    Joung Han Yim
    The Journal of Antibiotics, 2013, 66 : 559 - 561
  • [42] A new pseudodepsidone from the Antarctic lichen Stereocaulon alpinum and its antioxidant, antibacterial activity
    Bhattarai, Hari Datta
    Kim, Taikyung
    Oh, Hyuncheol
    Yim, Joung Han
    JOURNAL OF ANTIBIOTICS, 2013, 66 (09): : 559 - 561
  • [43] Composition of the essential oil and petroleum ether extract of Lycium chinense Miller fruits and antioxidant activity of its several extracts
    Chung, Ill-Min
    Nagella, Praveen
    Ahn, Young-Sup
    Kim, Seok-Ju
    Ahmad, Ateeque
    JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, 5 (25): : 5973 - 5981
  • [44] Cytotoxic effect and antioxidant activity of pterocarpans from Millettia aboensis root
    Ajaegbu, Eze E.
    Eboka, Chuks J.
    Okoye, Festus B. C.
    Proksch, Peter
    NATURAL PRODUCT RESEARCH, 2023, 37 (05) : 829 - 834
  • [45] Research on the Extraction of Flavonoids from Ginseng Root and its Ability in Antioxidant
    Ru ZHANG
    Bianling ZHANG
    Zhiyong LUO
    Medicinal Plant, 2013, (08) : 34 - 37
  • [46] Bioactivity-guided isolation of the major anthocyanin from Lycium ruthenicum Murr. fruit and its antioxidant activity and neuroprotective effects in vitro and in vivo
    Chen, Shasha
    Hu, Na
    Wang, Honglun
    Wu, Yongning
    Li, Guoliang
    FOOD & FUNCTION, 2022, 13 (06) : 3247 - 3257
  • [47] HPLC-MS/MS targeting analysis of phenolics metabolism and antioxidant activity of extractions from Lycium barbarum and its meal using different methods
    Shang, Ya-Fang
    Zhang, Tian-Hua
    Thakur, Kiran
    Zhang, Jian-Guo
    Armando Cespedes-Acuna, Carlos Leonardo
    Wei, Zhao-Jun
    FOOD SCIENCE AND TECHNOLOGY, 2022, 42
  • [48] New long-chain hydroxyalkyl ferulates from the root bark of Lycium chinense Mill.
    Pan, Shu
    Hou, Ai-Jun
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, 11 (07) : 681 - 685
  • [49] Three New Dimers and Two Monomers of Phenolic Amides from the Fruits of Lycium barbarum and Their Antioxidant Activities
    Gao, Kai
    Ma, Dongwei
    Cheng, Yan
    Tian, Xiangrong
    Lu, Yunyang
    Du, Xiaoying
    Tang, Haifeng
    Chen, Jianzong
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, 63 (04) : 1067 - 1075
  • [50] Antioxidant Activity of Pandanus amaryllifolius Leaf and Root Extract and its Application in Topical Emulsion
    Jimtaisong, Ampa
    Krisdaphong, Panvipa
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2013, 12 (03) : 425 - 431
12345