Microwave assisted synthesis of pyrazoline derivatives and their antiangiogenic and antioxidant activities

被引：0

作者：

Tengli, Anand Kumar

Badami, Shrishailappa ^{[1
]}

Kumar, B. R. Prashantha

Kumar, Santosh

Dongre, H.

Ravi, S.

Kumar, T. Durai Ananda

机构：

[1] JSS Coll Pharm, Dept Pharmaceut Chem, Ootacamund 643001, India

[2] Hindustan Photo Films Ltd, Ootacamund 643001, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 16卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrazolines were prepared both by conventional and microwave methods. Their, N-phenyl and acetyl derivatives were also prepared. The yields of these compounds by microwave method were found to be 70-85% for simple pyrazolines and 65-80% for N-phenyl substituted pyrazolines. Three compounds, II-4, III-6 and III-9 showed potent antiangiogenic activity by CAM assay. Weak or no antioxidant activity was observed for all the compounds by DPPH method.

引用

页码：333 / 336

页数：4

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