CNN for human exons and introns classification

被引:2
|
作者
Ben Nasr, Feriel [1 ]
Oueslati, Afef Elloumi [1 ,2 ]
机构
[1] Univ Tunis El Manar, SITI Lab, Natl Sch Engineers Tunis ENIT, BP 37, Tunis 1002, Tunisia
[2] Univ Carthage, Natl Sch Engineers Carthage ENICarthage, Elect Engn Dept, Carthage, Tunisia
关键词
Human DNA; Exon; Intron; Image Representation; Classification; CNN;
D O I
10.1109/SSD52085.2021.9429303
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Modeling properties and functions associated with DNA sequences is a very complex task in genomics. This task is more and more difficult when it concerns the human genome. This genome is composed with coding and non-coding regions which are not yet fully identified. Difficulties seen in this context are particularly related to the fact that 98% of the human genome is made up of non-coding zones. Therefore it seems evident that a powerful predictive model can have a huge advantage in advancing the exploration of the human genome. In this paper, we started from text representation of the DNA sequence to the representation of exons and introns by images to classify them. Here we are introducing a convolutional neural network model to classify human exons and introns. Our model has shown very good results concerning classification learning and testing rate which exceed 90%.
引用
收藏
页码:249 / 254
页数:6
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