INTRONS AND EXONS

被引：74
|
作者：
PATTHY, L
机构：
[1] Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 03期
关键词：
D O I：
10.1016/S0959-440X(94)90108-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Analysis of the exon-intron structures of genes, and a survey of the evolutionary distribution of mosaic proteins suggest that modularization of protein domains by intron insertions and their dispersal through exon-shuffling become significant on ly in higher eukaryotes. The appearance of this powerful evolutionary mechanism probably contributed significantly to the 'Big Bang' of metazoan radiation.
引用
收藏
页码：383 / 392
页数：10
相关论文
共 50 条
  • [1] INTRONS, EXONS AND IMMUNOGLOBULINS
    JEFFERIS, R
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1983, 8 (04) : 124 - 124
  • [2] COINCIDENT INDEXES OF EXONS AND INTRONS
    XU, J
    CHEN, RS
    LING, LJ
    SHEN, RQ
    SUN, J
    [J]. COMPUTERS IN BIOLOGY AND MEDICINE, 1993, 23 (04) : 333 - 343
  • [3] Exons, introns, and DNA thermodynamics
    Carlon, E
    Malki, ML
    Blossey, R
    [J]. PHYSICAL REVIEW LETTERS, 2005, 94 (17)
  • [4] INTRONS DIFFER FROM EXONS BY THEIR REDUNDANCY
    POPOVA, TG
    SADOVSKII, MG
    [J]. GENETIKA, 1995, 31 (10): : 1365 - 1369
  • [5] Length of exons and introns in protozoa genes
    Kabdullina, A. A.
    Ivachshenko, A. T.
    [J]. NEW BIOTECHNOLOGY, 2010, 27 : S42 - S42
  • [6] CNN for human exons and introns classification
    Ben Nasr, Feriel
    Oueslati, Afef Elloumi
    [J]. 2021 18TH INTERNATIONAL MULTI-CONFERENCE ON SYSTEMS, SIGNALS & DEVICES (SSD), 2021, : 249 - 254
  • [7] Exons-introns = lexons: In-frame concatenation of exons by PCR
    Tuohy, TMF
    Groden, J
    [J]. HUMAN MUTATION, 1998, 12 (02) : 122 - 127
  • [8] Comparison between phylogeny of introns and exons in primates
    Wang, N
    Chen, RS
    [J]. CHINESE SCIENCE BULLETIN, 1999, 44 (21): : 1940 - 1946
  • [9] EXONS, INTRONS, AND TALKING GENES - WILLS,C
    DIXON, B
    [J]. NEW STATESMAN & SOCIETY, 1992, 5 (210): : 36 - &
  • [10] Characterizing exons and introns by regularity of nucleotide strings
    Woods, Tonya
    Preeprem, Thanawadee
    Lee, Kichun
    Chang, Woojin
    Vidakovic, Brani
    [J]. BIOLOGY DIRECT, 2016, 11 : 6
12345