In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae

被引:25
|
作者
Welsh, L
Gaydos, C
Quinn, TC
机构
[1] JOHNS HOPKINS UNIV,SCH MED,DIV INFECT DIS,BALTIMORE,MD 21205
[2] NIAID,IMMUNOREGULAT LAB,BETHESDA,MD 20892
关键词
D O I
10.1128/AAC.40.1.212
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Thirteen strains of Chlamydia pneumoniae were evaluated for their in vitro susceptibilities to azithromycin, clarithromycin, erythromycin, and tetracycline. The MIC ranges were 0.125 to 0.5 mu g/ml for azithromycin, 0.031 to 1.0 mu g/ml for clarithromycin, 0.125 to 1.0 mu g/ml for erythromycin, and 0.125 to 1.0 mu g/ml for tetracycline, The ranges for the minimal lethal concentrations were 0.125 to 0.5 mu g/ml for azithromycin. 0.031 to 1.0 mu g/ml for clarithromycin, 0.125 to 1.0 mu g/ml for erythromycin, and 0.25 to 1.0 mu g/ml for tetracycline. Clarithromycin and azithromycin were the most active antibiotics against C. pneumoniae in vitro.
引用
收藏
页码:212 / 214
页数:3
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