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INVITRO ACTIVITIES OF 5 QUINOLONES AGAINST CHLAMYDIA-PNEUMONIAE
被引:55
|作者:
HAMMERSCHLAG, MR
[1
]
HYMAN, CL
[1
]
ROBLIN, PM
[1
]
机构:
[1] SUNY HLTH SCI CTR,DEPT MED,DIV INFECT DIS,BROOKLYN,NY 11203
关键词:
D O I:
10.1128/AAC.36.3.682
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The in vitro susceptibilities of 10 strains of Chlamydia pneumoniae were determined for five quinolones, including ciprofloxacin, ofloxacin, fleroxacin, temafloxacin, and sparfloxacin. Sparfloxacin was the most active compound tested, followed by ofloxacin and temafloxacin. Ciprofloxacin and fleroxacin were the least active. The use of HEp-2 cells for testing C. pneumoniae resulted in larger inclusions but essentially the same endpoints as were seen with use of HeLa 229 cells.
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页码:682 / 683
页数:2
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