Angioimmunoblastic T-cell lymphoma with autoimmune thrombocytopenia: A report of two cases

被引：6
|
作者：
Oka, Kuniyuki [1 ]
Nagayama, Reizo [1 ]
Yatabe, Yasushi [2 ]
Iijima, Shigeruko [1 ]
Mori, Naoyoshi [3 ]
机构：
[1] Mito Saiseikai Gen Hosp, Mito, Ibaraki 3114198, Japan
[2] Aichi Canc Ctr Hosp, Dept Pathol & Mol Diag, Nagoya, Aichi 464, Japan
[3] Nakatsugawa City Hosp, Gifu, Japan
来源：
PATHOLOGY RESEARCH AND PRACTICE | 2010年 / 206卷 / 04期
关键词：
Angioimmunoblastic T-cell lymphoma (AILT); Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD); Autoimmune thrombocytopenia (AIT); Platelet-associated immunoglobulin G (PAIgG); HYPERPLASTIC GERMINAL-CENTERS; IMMUNOBLASTIC LYMPHADENOPATHY;
D O I：
10.1016/j.prp.2009.04.002
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
We report two patients, a 68-year-old man (Case 1) and a 66-year-old man (Case 2), with polyclonal gammopathy, lymphadenopathy, thrombocytopenia, and high platelet-associated IgG (PAIgG) level. We initially diagnosed them as having angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). From confirmation of clear cells by careful observation and detection of rearrangement bands of T cell receptors by Southern blot hybridization analysis, we finally concluded that their diagnoses were compatible with angioimmunoblastic T-cell lymphoma (AILT). AILT with autoimmune thrombocytopenia (AIT) is very rare, and all the reported cases were Japanese ones. (C) 2009 Elsevier GmbH. All rights reserved.
引用
收藏
页码：270 / 275
页数：6
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