Angioimmunoblastic T-cell lymphoma: a rare subtype of peripheral T-cell lymphoma

被引：4

作者：

Rai, Manoj Ponadka ^{[1
]}

Bedi, Prabhjot Singh ^{[2
]}

Marinas, Edwin B. ^{[3
]}

Khan, Nazia Naz S. ^{[1
]}

机构：

[1] Michigan State Univ, Sparrow Hosp, B301,788 Serv Rd, E Lansing, MI 48824 USA

[2] UPMC East, 2775 Mosside Blvd, Monroeville, PA 15146 USA

[3] Sparrow Hosp, 1215 E Michigan Ave, Lansing, MI 48912 USA

来源：

CLINICAL CASE REPORTS | 2018年 / 6卷 / 04期

关键词：

Angioimmunoblastic T-cell lymphoma; autologous transplantation; Immunostaining (CD2; CD3; CD4; CD10; CXCL-13; PD1; BCL-6); nonhodgkin's lymphoma; T-cell lymphoma;

D O I：

10.1002/ccr3.1388

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Key Clinical Message Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL-13, PD1 often BCL-6 and CD20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD21 and CD23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline-containing regimens.

引用

页码：750 / 752

页数：3

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