Engineering Novel AAV Capsids for Cardiac Gene Delivery

被引:0
|
作者
Cheng, Ze [1 ]
Parvathaneni, Alekhya [1 ]
Reid, Christopher A. [1 ]
Nettesheim, Emily R. [1 ]
Easter, Emilee [1 ]
Greer-Short, Amara [1 ]
Feathers, Charles [1 ]
Chung, Tae Won [1 ]
Rodriguez, Neshel [1 ]
Lim, Beatriz [1 ]
Lin, JianMin [1 ]
Tingley, Whittemore [1 ]
Hoey, Timothy [1 ]
Ivey, Kathryn N. [1 ]
Lombardi, Laura [1 ]
机构
[1] Tenaya Therapeut, South San Francisco, CA USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
626
引用
收藏
页码:294 / 295
页数:2
相关论文
共 50 条
  • [21] Computationally guided AAV engineering for enhanced gene delivery
    Guo, Jingxuan
    Lin, Li F.
    Oraskovich, Sydney V.
    Jesus, Julio A. Rivera de
    Listgarten, Jennifer
    V. Schaffer, David
    TRENDS IN BIOCHEMICAL SCIENCES, 2024, 49 (05) : 457 - 469
  • [22] Rescue of Genetic Cardiac Arrhythmias by AAV Delivery of the Cardiac Calsequestrin Gene
    Newman, Mary
    Lawn, Richard
    James, Lucy
    Heffner, Garrett
    Chaivorapol, Christina
    Mei, Miranda
    Lawlor, Michael
    VandenAvond, Mark
    Napolitano, Carlo
    Priori, Silvia
    Prasad, Suyash
    Gray, John
    MOLECULAR THERAPY, 2018, 26 (05) : 70 - 70
  • [23] Applying Artificial Intelligence to Multi-Property Optimization of AAV Capsids for Neuronal Gene Delivery
    Deshpande, Mugdha
    Bloodgood, Daniel
    Diaz-Rohrer, Barbara
    Looby, Kailyn
    Hilton, Sarah
    Chen, Sam
    Sinai, Sam
    Lin, Kathy S.
    Kwasnieski, Jamie C.
    Veres, Adrian
    Kelsic, Eric
    MOLECULAR THERAPY, 2024, 32 (04) : 160 - 161
  • [24] Semi-rational engineering of next-generation AAV capsids for muscle gene therapy
    El Andari, J.
    Kraemer, C.
    Ayhan, S.
    Dietz, L.
    Grimm, D.
    HUMAN GENE THERAPY, 2019, 30 (11) : A7 - A7
  • [25] Novel AAV Capsids for Enhanced Gene Transfer to the Cerebellum, Spinal Cord, and Schwann Cells
    Chen, Xin
    Dong, Thomas
    Casy, Widler
    Hu, Yuhui
    Chen, Daphne
    McCown, Thomas
    Gray, Steven
    MOLECULAR THERAPY, 2021, 29 (04) : 157 - 157
  • [26] Engineering Novel AAV Capsids through Directed Evolution of the VP1u Region
    Cui, Mengtian
    Wang, Jiang-Hui
    McGowan, Jackson
    Yip, Mitchell
    Tai, Phillip W. L.
    Gao, Guangping
    MOLECULAR THERAPY, 2024, 32 (04) : 684 - 684
  • [27] Engineering of synthetic AAV capsids via rational assembly of "Virobytes"
    Boumezbeur, Ahmed-Hocine
    Grosse, Stefanie
    Grimm, Dirk
    HUMAN GENE THERAPY, 2014, 25 (11) : A83 - A83
  • [28] Novel DNA-Shuffled AAV Capsids Show Robust and Unique Gene Delivery and Expression Profiles in the CNS Via Intrathecal Injection
    Xiao, Bin
    Yuan, Zhenghua
    Yang, Lin
    Qiao, Chunping
    Li, Jianbin
    Li, Juan
    Xiao, Xiao
    MOLECULAR THERAPY, 2015, 23 : S239 - S240
  • [29] Identification of novel AAV capsids for treatment of lysosomal disorders
    Chen, Daphne
    Padegimas, Linas
    Zaric, Violeta
    Miller, Timothy J.
    Gray, Steven
    MOLECULAR GENETICS AND METABOLISM, 2018, 123 (02) : S31 - S31
  • [30] AAV-mediated gene delivery to the cardiac conduction system
    Jonker, T.
    Boender, A. R.
    Klerk, M.
    Barnett, P.
    De Vries, A. A. F.
    Christoffels, V. M.
    Boink, G. J. J.
    CARDIOVASCULAR RESEARCH, 2024, 120