Engineering of synthetic AAV capsids via rational assembly of "Virobytes"

被引:0
|
作者
Boumezbeur, Ahmed-Hocine [1 ,2 ]
Grosse, Stefanie [1 ,2 ]
Grimm, Dirk [1 ,2 ]
机构
[1] Univ Heidelberg Hosp, Dept Infect Dis Virol, Heidelberg, Germany
[2] Cluster Excellence CellNetworks, Heidelberg, Germany
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P085
引用
收藏
页码:A83 / A83
页数:1
相关论文
共 50 条
  • [1] Assembly of synthetic capsids
    Neranon, Kitjanit
    Ramstrom, Olof
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [2] Semi-rational engineering of next-generation AAV capsids for muscle gene therapy
    El Andari, J.
    Kraemer, C.
    Ayhan, S.
    Dietz, L.
    Grimm, D.
    HUMAN GENE THERAPY, 2019, 30 (11) : A7 - A7
  • [3] Development of Stabilized AAV Capsids for Vector Engineering
    Pacouret, Simon
    Eid, Fatma Elzahraa
    Donahoe, William
    Chan, Ken Y.
    Wu, Jason
    Zheng, Qingxia
    Keyes, Casey
    Brauer, Pamela
    Chen, Albert
    Chan, Yujia A.
    Deverman, Benjamin
    MOLECULAR THERAPY, 2023, 31 (04) : 24 - 24
  • [4] Engineering Novel AAV Capsids for Cardiac Gene Delivery
    Cheng, Ze
    Parvathaneni, Alekhya
    Reid, Christopher A.
    Nettesheim, Emily R.
    Easter, Emilee
    Greer-Short, Amara
    Feathers, Charles
    Chung, Tae Won
    Rodriguez, Neshel
    Lim, Beatriz
    Lin, JianMin
    Tingley, Whittemore
    Hoey, Timothy
    Ivey, Kathryn N.
    Lombardi, Laura
    MOLECULAR THERAPY, 2022, 30 (04) : 294 - 295
  • [5] Engineering Novel AAV Capsids for Cardiac Gene Delivery
    Cheng, Ze
    Easter, Emilee
    Feathers, Charles
    Leong, Jackson
    Lim, Beatriz
    Jones, Samantha
    Woods, Joe
    Parvathaneni, Alekhya
    Reid, Christopher A.
    Nettesheim, Emily R.
    Doerner, Karl
    Lin, JianMin
    Jing, Frank
    Tingley, Whittemore
    Hoey, Timothy
    Ivey, Kathryn N.
    Lombardi, Laura M.
    MOLECULAR THERAPY, 2023, 31 (04) : 238 - 238
  • [6] Engineering novel AAV capsids for cardiac gene delivery
    Cheng, Z.
    Parvathaneni, A.
    Easter, E.
    Reid, C. A.
    Nettesheim, E. R.
    Zhou, H.
    Xu, E.
    Lin, J.
    Tingley, W.
    Hoey, T.
    Ivey, K. N.
    Lombardi, L. M.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A30 - A31
  • [7] Benchmarking Natural and Synthetic AAV Capsids for Neutralizing Antibody Evasion
    Donahoe, William
    Pacouret, Simon
    Brauer, Pamela P.
    Harvey, John W.
    Pirtle, Catherine P.
    Chan, Ken Y.
    Chan, Yujia A.
    Deverman, Benjamin E.
    MOLECULAR THERAPY, 2024, 32 (04) : 725 - 725
  • [8] Expanding the Serotype Frontier: Design of Synthetic AAV Capsids with Artificial Intelligence
    Sinai, Sam
    Brookes, David
    Chan, Jeffrey
    Mijalis, Alex
    Kern, Alex
    Prasad, Neha
    Sternlieb, Eodore
    Damani, Farhan
    Lin, Kathy S.
    Kwasnieski, Jamie
    Veres, Adrian
    Kelsic, Eric
    MOLECULAR THERAPY, 2024, 32 (04) : 691 - 692
  • [9] Characterization of Engineered AAV Capsids for Improved Transduction Efficiency through Rational Design
    Hu, Jingjie
    Theofilas, Panos
    Bainbridge, Travis
    Kim, Yoon Min
    Bulutoglu, Beyza
    Foreman, Oded
    Chen, Honglin
    Lattanzi, Annalisa
    MOLECULAR THERAPY, 2024, 32 (04) : 477 - 477
  • [10] Hierarchical assembly is more robust than egalitarian assembly in synthetic capsids
    Wei, Wei - Shao
    Trubiano, Anthony
    Sigl, Christian
    Paquay, Stefan
    Dietz, Hendrik
    Hagan, Michael F.
    Fraden, Seth
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 121 (07)