Directed Evolution of AAV9 Peptide Display Libraries Identifies a Family of Cross-Species Variants with Enhanced Brain Tropism in Non-Human Primates and Mice Following Systemic Administration

被引：0
|
作者：
Moyer, Tyler [1 ]
Li, Jiangyu [1 ]
Laks, Dan R. [1 ]
Child, Matthew A. [1 ]
Tyson, Katherine [1 ]
Kaur, Rupinderjit [1 ]
Ren, Xiao-Qin [1 ]
Sayed-Zahid, Ambreen [1 ]
Grannon, Michael [1 ]
Chung, Charlotte Hiu-Yan [1 ]
Pande, Nilesh [1 ]
Thompson, Jeff [1 ]
Wang, Wei [1 ]
Hasson, Samuel [1 ]
Hefferan, Michael [1 ]
Nonnenmacher, Mathieu [1 ]
机构：
[1] Voyager Therapeut, Cambridge, MA USA
来源：
MOLECULAR THERAPY | 2022年 / 30卷 / 04期
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D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
1198
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收藏
页码：556 / 557
页数：2
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