Directed Evolution of an AAV5 Capsid Library Identifies a Variant with Enhanced Transduction in Non-Human Primate and Rodent Brain Following Systemic Administration

被引:0
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作者
Nonnenmacher, Mathieu E. [1 ]
Ren, Amy Z. [1 ]
Wang, Wei [1 ]
Child, Matthew A. [1 ]
Ren, Xiao-Qin [1 ]
Tyson, Katherine [1 ]
Laguna-Torres, Jessenia [1 ]
Kulkarni, Anupriya [1 ]
Pande, Nilesh [1 ]
Sayed-Zahid, Ambreen [1 ]
Chung, Charlotte H. Y. [1 ]
Hefferan, Michael [1 ]
Moyer, Tyler [1 ]
Maura, Damien [1 ]
机构
[1] Voyager Therapeut, Cambridge, MA USA
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中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
129
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收藏
页码:69 / 69
页数:1
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