Optimizing Atrial Electrogram Classification Based on Local Ablation Outcome in Human Atrial Fibrillation

被引:3
|
作者
Bezerra, Arthur S. [1 ]
Yoneyama, Takashi [1 ]
Soriano, Diogo C. [2 ]
Luongo, Giorgio [3 ]
Li, Xin [4 ]
Ravelli, Flavia [5 ]
Mase, Michela [6 ]
Chu, Gavin S. [4 ]
Stafford, Peter J. [4 ]
Schlindwein, Fernando S. [4 ]
Ng, G. Andre [4 ]
de Almeida, Tiago P. [1 ,4 ]
机构
[1] Aeronaut Inst Technol, Praca Marechal Eduardo Gomes 50, BR-12228900 Sao Jose Dos Campos, SP, Brazil
[2] Fed ABC Univ, Santo Andre, SP, Brazil
[3] Karlsruhe Inst Technol, Karlsruhe, Germany
[4] Univ Leicester, Leicester, Leics, England
[5] Univ Trento, Trento, Italy
[6] Eurac Res, Bolzano, Italy
来源
2020 COMPUTING IN CARDIOLOGY | 2020年
基金
巴西圣保罗研究基金会; 英国医学研究理事会;
关键词
CATHETER; LENGTH;
D O I
10.22489/CinC.2020.131
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Changes in atrial fibrillation cycle length (AF-CL) are broadly used as a 'ground truth' to assess the effect of substrate modification during AF ablation. This work sought to optimize thresholds for changes in coronary sinus CL (CS-CL) after local ablation using different atrial electrogram (AEG)-derived markers. 834 AEGs were collected from 11 patients undergoing persAF ablation. CS-CL was measured before and after each ablation point. Five AEG-derived markers were tested as classifiers for CS-CL changes: ICL (Biosense Webster), CFE-Mean (St. Jude Medical), Wave Similarity, Shannon Entropy and AEG-CL. The area under the receiver operating characteristic (AUROC) curve was used to assess the quality of classification for each marker. Maximum AUROC was found at threshold values between 9 and 14 ms in all markers, except for Shannon Entropy. The average AUROC of the five markers reached a maximum of 0.60 at a threshold value of 10 ms. The 10 ms threshold is suggested as a starting setpoint for future studies seeking to identify AF ablation targets based on an objective 'ground truth'.
引用
收藏
页数:4
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