Preparation of 90Y by the 90Sr-90Y generator for medical purpose

被引：27
|
作者：
Malja, S [1 ]
Schomacker, K
Malja, E
机构：
[1] Inst Nucl Phys, Tirana, Albania
[2] Inst Nucl Med, Cologne, Germany
[3] Univ La Sapienza, Fac Med & Surg, Rome, Italy
来源：
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2000年 / 245卷 / 02期
关键词：
Chemical purity - Injectables - Labelings - Radiochemical purity - Solution pH;
D O I：
10.1023/A:1006743428757
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The production of Y-90 by Sr-90-Y-90 generator was studied. Sr-90 was adsorbed on a column with Aminex A-5 resin. The daughter radionuclide Y-90 was eluted with 0.7M alpha-hydroxyisoburyrate (alpha-HIB, pH 5.4). Radionuclidic, radiochemical and chemical purities were >98% and yield >85%. After converting into chloride form (YCl3)-Y-90-solution (pH:1) was used for preparing injectable yttrium citrate and labeling some other radiopharmaceuticals. Furthermore, a fast ITLC-method for the determination of Sr-90 in Y-90-eluate was developed.
引用
收藏
页码：403 / 406
页数：4
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