Functions of HLA-G in the immune system

被引：32

作者：

Favier, B. ^{[1
]}

LeMaoult, J. ^{[1
]}

Carosella, E. D. ^{[1
]}

机构：

[1] Inst Univ Hematol, Hop St Louis, Serv Rech Hemato Immunol, Direct Sci Vivant,Dept Rech Med,Commissariat Ener, F-75010 Paris, France

来源：

TISSUE ANTIGENS | 2007年 / 69卷

关键词：

HLA-G; immune inhibition; tolerance;

D O I：

10.1111/j.1399-0039.2006.763_6.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has tolerogenic functions and acts on cells of both innate and adaptive immunity. The molecular mechanism leading to tolerance involves the interaction between HLA-G and inhibitory receptors that are expressed at the surface of immune cells. In this review, we will briefly summarize the key advances on the relationships between HLA-G and the immune system and their consequences in pathology.

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页码：150 / 152

页数：3

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