Click-Chemistry Cross-Linking of Hyaluronan Graft Copolymers

被引：6

作者：

Saletti, Mario ^{[1
]}

Paolino, Marco ^{[1
]}

Ballerini, Lavinia ^{[1
]}

Giuliani, Germano ^{[1
]}

Leone, Gemma ^{[1
]}

Lamponi, Stefania ^{[1
]}

Andreassi, Marco ^{[1
]}

Bonechi, Claudia ^{[1
]}

Donati, Alessandro ^{[1
]}

Piovani, Daniele ^{[2
]}

Schieroni, Alberto Giacometti ^{[2
]}

Magnani, Agnese ^{[1
]}

Cappelli, Andrea ^{[1
]}

机构：

[1] Univ Siena, Dipartimento Biotecnol Chim & Farm Dipartimento E, Via Aldo Moro 2, I-53100 Siena, Italy

[2] Ist Sci & Tecnol Chim G Natta SCITEC CNR, Via A Corti 12, I-20133 Milan, Italy

来源：

PHARMACEUTICS | 2022年 / 14卷 / 05期

关键词：

hyaluronic acid; ferulic acid; click-chemistry; crosslinking; hydrogel; FERULIC ACID; CELL; STATES; WALLS; WATER;

D O I：

10.3390/pharmaceutics14051041

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

An easy and viable crosslinking procedure by click-chemistry (click-crosslinking) of hyaluronic acid (HA) was developed. In particular, the clickable propargyl groups of hyaluronane-based HA-FA-Pg graft copolymers showing low and medium molecular weight values were exploited in crosslinking by click-chemistry by using a hexa(ethylene glycol) spacer. The resulting HA-FA-HEG-CL materials showed an apparent lack of in vitro cytotoxic effects, tuneable water affinity, and rheological properties according to the crosslinking degree that suggests their applicability in different biomedical fields.

引用

页数：24

共 50 条

[41] Polypropylene-based graft copolymers via CuAAC click chemistry
Acik, G.
Sey, E.
Tasdelen, M. A.
[J]. EXPRESS POLYMER LETTERS, 2018, 12 (05): : 418 - 428
[42] A "click-chemistry" approach to cellulose-based hydrogels
Koschella, Andreas
Hartlieb, Matthias
Heinze, Thomas
[J]. CARBOHYDRATE POLYMERS, 2011, 86 (01) : 154 - 161
[43] Stabilized Neurotensin-Based Radiopeptidomimetics by Click-Chemistry
Mascarin, A.
Valverde, I. E.
Mindt, T. L.
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 : S322 - S322
[44] Application of click-chemistry bioconjugation methods in the imaging of cancer
Lewis, Jason
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[45] Development of a Click-Chemistry Reagent Compatible with Mass Cytometry
Shaklee, Jessica
Srivastava, Kriti
Brown, Heather
Arriaga, Edgar A.
Pierre, Valerie C.
van Berlo, Jop H.
[J]. SCIENTIFIC REPORTS, 2018, 8
[46] A Hitchhiker's Guide to Click-Chemistry with Nucleic Acids
Fantoni, Nicolo Zuin
El-Sagheer, Afaf H.
Brown, Tom
[J]. CHEMICAL REVIEWS, 2021, 121 (12) : 7122 - 7154
[47] Development of a Click-Chemistry Reagent Compatible with Mass Cytometry
Jessica Shaklee
Kriti Srivastava
Heather Brown
Edgar A. Arriaga
Valerie C. Pierre
Jop H. van Berlo
[J]. Scientific Reports, 8
[48] Cellulose surface grafting with polycaprolactone by heterogeneous click-chemistry
Krouit, Mohammed
Bras, Julien
Belgacem, Mohamed Naceur
[J]. EUROPEAN POLYMER JOURNAL, 2008, 44 (12) : 4074 - 4081
[49] The Click-chemistry to join the ADAM10 substrates
Saurty, Mirca
Sanson, Romain
Amrane, Rania
Rubinstein, Eric
[J]. M S-MEDECINE SCIENCES, 2016, 32 (10): : 836 - 839
[50] THERMAL CROSS-LINKING OF STYRENE PARA-METHYLSTYRENE COPOLYMERS
SCHRODER, UKO
[J]. MAKROMOLEKULARE CHEMIE-MACROMOLECULAR CHEMISTRY AND PHYSICS, 1987, 188 (11): : 2775 - 2787

← 1 2 3 4 5 →