Antimicrobial activities of daptomycin, vancomycin, and oxacillin in human monocytes and of daptomycin in combination with gentamicin and/or rifampin in human monocytes and in broth against Staphylococcus aureus

被引：44
|
作者：
Baltch, Aldona L. [1 ]
Ritz, William J.
Bopp, Lawrence H.
Michelsen, Phyllis B.
Smith, Raymond P.
机构：
[1] Stratton VA Med Ctr, Infect Dis Sect 111D, Albany, NY 12208 USA
[2] Albany Med Coll, Albany, NY 12208 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 04期
关键词：
D O I：
10.1128/AAC.00973-06
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We investigated the anti staphylococcal activity of daptomycin, vancomycin, oxacillin, gentamicin, and rifampin in human monocyte-derived macrophages. Compared with vancomycin and oxacillin, daptomycin had the most rapid and greatest antibacterial activity, but that of oxacillin was most sustained. The combination of daptomycin, gentamicin, and rifampin was most effective intracellularly, while daptomycin plus gentamicin and the three-drug combination were most effective extracellularly, completely eliminating viable Staphylocorcus aureus.
引用
收藏
页码：1559 / 1562
页数：4
相关论文
共 50 条
  • [21] INVITRO STUDY OF THE COMBINATION OF RIFAMPIN WITH OXACILLIN AGAINST STAPHYLOCOCCUS-AUREUS
    VANDERAUWERA, P
    KLASTERSKY, J
    REVIEWS OF INFECTIOUS DISEASES, 1983, 5 : S509 - S514
  • [22] INVITRO ACTIVITY OF RIFAMPIN IN COMBINATION WITH OXACILLIN AGAINST STAPHYLOCOCCUS-AUREUS
    TRACZEWSKI, MM
    GOLDMANN, DA
    MURPHY, P
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1983, 23 (04) : 571 - 576
  • [23] In vitro testing of daptomycin plus rifampin against methicillin-resistant Staphylococcus aureus resistant to rifampin
    Khasawneh, FaisalA.
    Ashcraft, Deborah S.
    Pankey, George A.
    SAUDI MEDICAL JOURNAL, 2008, 29 (12) : 1726 - 1729
  • [24] Detection of Synergistic Antimicrobial Activities of Ceftaroline, Telavancin, Daptomycin, and Vancomycin Against Methicillin-Resistant Staphylococcus aureus Strains in Intensive Care
    Sanal, Laser
    Yilmaz, Neziha
    Uludag, Hatice
    Ozturk, Reyhan
    Sen, Suha
    Cesur, Salih
    JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2018, 11 (11)
  • [25] Comparison of Commercial Antimicrobial Susceptibility Test Methods for Testing of Staphylococcus aureus and Enterococci against Vancomycin, Daptomycin, and Linezolid
    Riedel, Stefan
    Neoh, Kar Mun
    Eisinger, Stephen W.
    Dam, Lisa M.
    Tekle, Tsigereda
    Carroll, Karen C.
    JOURNAL OF CLINICAL MICROBIOLOGY, 2014, 52 (06) : 2216 - 2222
  • [26] Dalbavancin, Vancomycin and Daptomycin Alone and in Combination with Cefazolin against Resistant Phenotypes of Staphylococcus aureus in a Pharmacokinetic/Pharmacodynamic Model
    Abdul-Mutakabbir, Jacinda C.
    Kebriaei, Razieh
    Stamper, Kyle C.
    Sheikh, Zain
    Maassen, Philip T.
    Lev, Katherine L.
    Rybak, Michael J.
    ANTIBIOTICS-BASEL, 2020, 9 (10): : 1 - 12
  • [27] Efficacy of vancomycin and daptomycin against Staphylococcus aureus isolates collected over 29 years
    Appleman, Maria D.
    Citron, Diane M.
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2010, 66 (04) : 441 - 444
  • [28] Evaluation of Telavancin Activity versus Daptomycin and Vancomycin against Daptomycin-Nonsusceptible Staphylococcus aureus in an In Vitro Pharmacokinetic/Pharmacodynamic Model
    Steed, Molly E.
    Vidaillac, Celine
    Rybak, Michael J.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (02) : 955 - 959
  • [29] Evaluation of tedizolid against Staphylococcus aureus and enterococci with reduced susceptibility to vancomycin, daptomycin or linezolid
    Barber, Katie E.
    Smith, Jordan R.
    Raut, Animesh
    Rybak, Michael J.
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2016, 71 (01) : 152 - 155
  • [30] Combination therapy with daptomycin, vancomycin, and rifampin for recurrent, severe bone and prosthetic joint infections involving methicillin-resistant Staphylococcus aureus
    Antony, Suresh J.
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2006, 38 (04) : 293 - 295
12345