Clinical and Molecular Epidemiology of Escherichia coli Sequence Type 131 among Hospitalized Patients Colonized Intestinally with Fluoroquinolone-Resistant E-coli

被引：7
|
作者：
Han, Jennifer H. [1 ,2 ,3 ]
Johnston, Brian [5 ,6 ]
Nachamkin, Irving [4 ]
Tolomeo, Pam [2 ]
Bilker, Warren B. [2 ,3 ]
Mao, Xiangqun [2 ]
Clabots, Connie [5 ,6 ]
Lautenbach, Ebbing [1 ,2 ,3 ]
Johnson, James R. [5 ,6 ]
机构：
[1] Univ Penn, Dept Med, Div Infect Dis, Perelman Sch Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Ctr Clin Epidemiol & Biostat, Perelman Sch Med, Philadelphia, PA 19104 USA
[3] Univ Penn, Dept Biostat & Epidemiol, Perelman Sch Med, Philadelphia, PA 19104 USA
[4] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA 19104 USA
[5] Minneapolis Vet Affairs Med Ctr, Minneapolis, MN USA
[6] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2014年 / 58卷 / 11期
基金：
美国国家卫生研究院;
关键词：
RISK-FACTORS; ST131; INFECTIONS; DOMINANT; STRAINS; B2;
D O I：
10.1128/AAC.03256-14
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study examined molecular and epidemiologic factors associated with Escherichia coli sequence type 131 (ST131) among hospitalized patients colonized intestinally with fluoroquinolone (FQ)-resistant E. coli between 2002 and 2004. Among 86 patients, 21 (24%) were colonized with ST131. The proportion of ST131 isolates among colonizing isolates increased significantly over time, from 8% in 2002 to 50% in 2004 (P = 0.003). Furthermore, all 19 clonally related isolates were ST131. Future studies should identify potential transmissibility differences between ST131 and non-ST131 strains.
引用
收藏
页码：7003 / 7006
页数：4
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