Induction of tumor necrosis factor-α mRNA in the kidney of the mouse chronic hepatitis model

被引：1
|
作者：
Okamoto, T
Furuya, M
Yamakawa, T
Yamamura, K
Hino, O
机构：
[1] Japanese Fdn Canc Res, Inst Canc, Dept Expt Pathol, Toshima Ku, Tokyo 170, Japan
[2] Nippon Chemiphar Co Ltd, Res Labs, Misato, Saitama 341, Japan
[3] Kumamoto Univ, Sch Med, Inst Mol Embryol & Genet, Kumamoto 862, Japan
来源：
JAPANESE JOURNAL OF PHARMACOLOGY | 1998年 / 76卷 / 01期
关键词：
transgenic mouse; interferon; tumor necrosis factor;
D O I：
10.1254/jjp.76.97
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Previously we reported the induction of tumor necrosis factor (TNF)-alpha mRNA in the liver of interferon (IFN)-gamma transgenic mouse, which might be the result of IFN-gamma gene expression. In the present study, IFN-gamma mRNA was induced in the liver, kidney and lung. TNF-alpha mRNA was, however, induced in the liver and kidney, but not in the lung. Induction of interleukin (IL)-2 and IL-1 beta mRNA was lacking in any of these organs. The present result showed the induction of TNF-alpha mRNA expression in the kidney of transgenic mouse.
引用
收藏
页码：97 / 99
页数：3
相关论文
共 50 条
  • [41] Induction of tumor necrosis factor-α by cefodizime in U-937 cells
    Guerra-Infante, FM
    Zamora-Ruíz, A
    López-Hurtado, M
    Flores-Medina, S
    REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, 2001, 53 (04): : 335 - 339
  • [42] Myocardial expression of tumor necrosis factor-α and tumor necrosis factor-α converting enzyme in human myocarditis
    Satoh, M
    Nakamura, M
    Satoh, H
    Segawa, I
    Masuda, T
    Hiramori, K
    CIRCULATION, 1999, 100 (18) : 381 - 381
  • [43] Induction of mRNA for tumor necrosis factor-α and interleukin-1β in mice brain, spleen and liver in an animal model of Shigella-related seizures
    Nofech-Mozes, Y
    Yuhas, Y
    Kaminsky, E
    Weizman, A
    Ashkenazi, S
    ISRAEL MEDICAL ASSOCIATION JOURNAL, 2000, 2 (02): : 86 - 90
  • [44] Inhibition of tumour necrosis factor-α in patients with chronic hepatitis C infection
    C. Zavos
    J. Kountouras
    N. Zavos
    D. Chatzopoulos
    Clinical Rheumatology, 2007, 26 : 283 - 283
  • [45] Inhibition of tumour necrosis factor-α in patients with chronic hepatitis C infection
    Zavos, C.
    Kountouras, J.
    Zavos, N.
    Chatzopoulos, D.
    CLINICAL RHEUMATOLOGY, 2007, 26 (02) : 283 - 283
  • [46] Tumor necrosis factor-α enhances the expression of vascular endothelial growth factor in a mouse orthodontic tooth movement model
    Noguchi, Takahiro
    Kitaura, Hideki
    Marahleh, Aseel
    Ohori, Fumitoshi
    Nara, Yasuhiko
    Pramusita, Adya
    Kinjo, Ria
    Ma, Jinghan
    Kanou, Kayoko
    Mizoguchi, Itaru
    JOURNAL OF DENTAL SCIENCES, 2022, 17 (01) : 415 - 420
  • [47] Tumor Necrosis Factor-α-Induced Ototoxicity in Mouse Cochlear Organotypic Culture
    Wu, Qian
    Wang, Guo-Peng
    Xie, Jing
    Guo, Jing-Ying
    Gong, Shu-Sheng
    PLOS ONE, 2015, 10 (05):
  • [48] Interleukin-1β and tumor necrosis factor-α suppress dexamethasone induction of glutamine synthetase in primary mouse astrocytes
    Huang, TL
    O'Banion, MK
    JOURNAL OF NEUROCHEMISTRY, 1998, 71 (04) : 1436 - 1442
  • [49] Tumor necrosis factor-α-induced cytoprotective mechanisms in cardiomyocytes -: Analysis by mRNA phenotyping
    Sharma, HS
    Weisensee, D
    Löw-Friedrich, I
    MYOCARDIAL PRESERVATION, PRECONDITIONING, AND ADAPTATION, 1996, 793 : 267 - 281
  • [50] Influence of transforming growth factor-β1 and tumor necrosis factor-α genes polymorphisms on the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis C patients
    Radwan, Mohamed I.
    Pasha, Heba F.
    Mohamed, Rasha H.
    Hussien, Hala I. M.
    El-Khshab, Mohamed N.
    CYTOKINE, 2012, 60 (01) : 271 - 276
12345