Ionic liquid catalyzed solvent-free synthesis of chalcone and its derivatives under mild conditions

被引：4
|
作者：
Zhao, Qiu [1 ,2 ]
Wang, Gang [2 ,3 ]
Liao, Fuxia [2 ]
Sha, Yifan [1 ]
Xu, Fei [2 ]
Li, Chunshan [2 ,3 ]
Li, Zengxi [2 ,3 ]
Cao, Yijun [1 ]
机构：
[1] Zhengzhou Univ, Sch Chem Engn & Energy, Zhengzhou 450001, Peoples R China
[2] Chinese Acad Sci, State Key Lab Multiphase Complex Syst, Beijing Key Lab Ion Liquids Clean Proc, Key Lab Green Proc & Engn,Inst Proc Engn, Beijing 100190, Peoples R China
[3] Univ Chinese Acad Sci, Sch Chem Sci, Beijing 100049, Peoples R China
来源：
CHINESE JOURNAL OF CHEMICAL ENGINEERING | 2021年 / 33卷
基金：
国家自然科学基金重大项目; 中国国家自然科学基金;
关键词：
Ionic liquid; Chalcone; Aldol reaction; Kinetic model; OPTICAL-PROPERTIES; HIGH-YIELD; ONE-STEP;
D O I：
10.1016/j.cjche.2020.09.013
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
An ionic liquid (IL) catalyzed solvent-free process was developed for the direct synthesis of chalcone and its derivatives by using substituted acetophenones and benzaldehydes via aldol reaction under mild conditions. A series of acidic and basic ILs were selected and screened. The influences of cations and reaction conditions on product yield and selectivity were systematically investigated. The [Bmim]OH was identified as the optimal IL, with the highest yield and selectivity reaching up to 96.7% and 100%, respectively. A reaction mechanism-based kinetic model was established and regressed with experimental data, revealing the beta-Hydroxylketone dehydrolysis with activation barrier of 37.8 kJ.mol(-1) was observed as the rate-controlling step. (C) 2020 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All righs reserved
引用
收藏
页码：160 / 166
页数：7
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