Efficient synthesis of quinoxaline derivatives catalyzed by p-toluenesulfonic acid under solvent-free conditions

被引:27
|
作者
Shi, Da-Qing [1 ,2 ]
Dou, Guo-Lan [1 ]
机构
[1] Xuzhou Normal Univ, Coll Chem & Chem Engn, Xuzhou 221116, Peoples R China
[2] Suzhou Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215006, Peoples R China
关键词
p-toluenesulfonic acid; quinoxaline; room temperature; solvent-free conditions;
D O I
10.1080/00397910802136664
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of quinoxaline derivatives were efficiently synthesized in excellent yields by the reaction of 1,2-diamines and 1,2-diketones with grinding catalyzed by p-toluenesulfonic acid under solvent-free conditions at room temperature. Compared with the classical synthetic method, this new method has the advantages of convenient manipulation and environmental friendliness.
引用
收藏
页码:3329 / 3337
页数:9
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