Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

被引：6

作者：

Borsa, Baris A. ^{[1
]}

Sudagidan, Mert ^{[2
]}

Aldag, Mehmet E. ^{[3
]}

Baris, Isik I. ^{[4
]}

Acar, Elif E. ^{[2
]}

Acuner, Cagatay ^{[5
]}

Kavruk, Murat ^{[6
]}

Ozalp, Veli C. ^{[7
]}

机构：

[1] Linkoping Univ, Dept Phys Chem & Biol IFM, Nucle Acid Technol Lab, SE-58183 Linkoping, Sweden

[2] Konya Food & Agr Univ, Kit Argem Res Ctr, TR-42080 Meram, Konya, Turkey

[3] Corlu State Hosp, Dept Med Microbiol, Tekirdag, Turkey

[4] Cakmak Erdem Hosp, Dept Pathol, Istanbul, Turkey

[5] Yeditepe Univ, Med Sch, Dept Med Microbiol, Istanbul, Turkey

[6] Turkish Stand Inst TSE, Test & Calibrat Ctr, TR-41400 Kocaeli, Turkey

[7] Atilim Univ, Med Sch, Dept Med Biol, TR-06830 Ankara, Turkey

来源：

RSC MEDICINAL CHEMISTRY | 2021年 / 12卷 / 03期

关键词：

D O I：

10.1039/d0md00347f

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for S. aureus infection.

引用

页码：380 / 383

页数：4

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