Detection of SARS-CoV-2 at the point of care

被引:24
|
作者
Loeffelholz, Michael J. [1 ]
Tang, Yi-Wei [2 ]
机构
[1] Cepheid, Sunnyvale, CA USA
[2] Danaher Diagnost Platform, Shanghai, Peoples R China
关键词
COVID-19; home testing; nucleic acid amplification testing; POCT; pooled specimen screening; rapid antigen testing; SARS-CoV-2; XPERT XPRESS SARS-COV-2; OF-CARE; TESTS; PERFORMANCE; INFECTION; IMPACT;
D O I
10.4155/bio-2021-0078
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of COVID-19. Testing for SARS-CoV-2 infection is a critical element of the public health response to COVID-19. Point-of-care (POC) tests can drive patient management decisions for infectious diseases, including COVID-19. POC tests are available for the diagnosis of SARS-CoV-2 infections and include those that detect SARS-CoV-2 antigens as well as amplified RNA sequences. We provide a review of SARS-CoV-2 POC tests including their performance, settings for which they might be used, their impact and future directions. Further optimization and validation, new technologies as well as studies to determine clinical and epidemiological impact of SARS-CoV-2 POC tests are needed.
引用
收藏
页码:1213 / 1223
页数:11
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