BDNF controls object recognition memory reconsolidation

被引:44
|
作者
Radiske, Andressa [1 ]
Rossato, Janine I. [1 ]
Gonzalez, Maria Carolina [1 ]
Kohler, Cristiano A. [1 ]
Bevilaqua, Lia R. [1 ]
Cammarota, Martin [1 ]
机构
[1] Univ Fed Rio Grande do Norte, Brain Inst, Memory Res Lab, Av Nascimento Castro 2155, BR-59056450 Natal, RN, Brazil
关键词
Anisomycin; alpha-amanitin; Muscimol; Novelty; Retrieval; MEDIAL PREFRONTAL CORTEX; LONG-TERM-MEMORY; SPATIAL MEMORY; PROTEIN-SYNTHESIS; TRANSLATION MACHINERY; DORSAL HIPPOCAMPUS; PERIRHINAL CORTEX; MAMMALIAN TARGET; CONSOLIDATION; RETRIEVAL;
D O I
10.1016/j.nlm.2017.02.018
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Reconsolidation restabilizes memory after reactivation. Previously, we reported that the hippocampus is engaged in object recognition memory reconsolidation to allow incorporation of new information into the original engram. Here we show that BDNF is sufficient for this process, and that blockade of BDNF function in dorsal CA(1) impairs updating of the reactivated recognition memory trace. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:79 / 84
页数:6
相关论文
共 50 条
  • [21] Infusion of protein synthesis inhibitors in the entorhinal cortex blocks consolidation but not reconsolidation of object recognition memory
    Lima, Ramon H.
    Rossato, Janine I.
    Furini, Cristiane R.
    Bevilaqua, Lia R.
    Izquierdo, Ivan
    Cammarota, Martin
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2009, 91 (04) : 466 - 472
  • [22] Nucleus reuniens of the thalamus controls fear memory reconsolidation
    Troyner, Fernanda
    Bertoglio, Leandro Jose
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2021, 177
  • [23] Rapid eye movement sleep deprivation disrupts consolidation but not reconsolidation of novel object recognition memory in rats
    Chen, Lin
    Tian, Shaowen
    Ke, Jie
    NEUROSCIENCE LETTERS, 2014, 563 : 12 - 16
  • [24] Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
    Francis, Beverly M.
    Kim, John
    Barakat, Meredith E.
    Fraenkl, Stephan
    Yuecel, Yeni H.
    Peng, Shiyong
    Michalski, Bernadeta
    Fahnestock, Margaret
    McLaurin, JoAnne
    Mount, Howard T. J.
    NEUROBIOLOGY OF AGING, 2012, 33 (03) : 555 - 563
  • [25] Arousal and Stress Effects on Consolidation and Reconsolidation of Recognition Memory
    Mouna Maroun
    Irit Akirav
    Neuropsychopharmacology, 2008, 33 : 394 - 405
  • [26] Hippocampal noradrenergic activation is necessary for object recognition memory consolidation and can promote BDNF increase and memory persistence
    Mello-Carpes, Pamela B.
    de Vargas, Liane da Silva
    Gayer, Mateus Cristofari
    Roehrs, Rafael
    Izquierdo, Ivan
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2016, 127 : 84 - 92
  • [27] Arousal and stress effects on consolidation and reconsolidation of recognition memory
    Maroun, Mouna
    Akirav, Irit
    NEUROPSYCHOPHARMACOLOGY, 2008, 33 (02) : 394 - 405
  • [28] BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory
    Hopkins, Michael E.
    Bucci, David J.
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2010, 94 (02) : 278 - 284
  • [29] Stress impairs consolidation of recognition memory after blocking drug memory reconsolidation
    Zhao, Xiaojie
    Li, Yang
    Peng, Tao
    Seese, Ronald R.
    Wang, Zhenyuan
    NEUROSCIENCE LETTERS, 2011, 501 (01) : 50 - 54
  • [30] Recognition memory reconsolidation requires hippocampal Zif268
    Maria Carolina Gonzalez
    Janine I. Rossato
    Andressa Radiske
    Marina Pádua Reis
    Martín Cammarota
    Scientific Reports, 9