Production of teicoplanin by a mutant of Actinoplanes teicomyceticus

被引：14
|
作者：
Lee, JC
Park, HR
Park, DJ
Son, KH
Yoon, KH
Kim, YB
Kim, CJ
机构：
[1] Korea Res Inst Biosci & Biotechnol, Taejon 305600, South Korea
[2] Woosong Univ, Sch Food Sci & Biotechnol, Taejon, South Korea
[3] Korea Univ, Grad Sch Biotechnol, Seoul 136701, South Korea
来源：
BIOTECHNOLOGY LETTERS | 2003年 / 25卷 / 07期
关键词：
Actinoplanes teicomyceticus; Diaion HP-20; fermentation; mutation; teicoplanin;
D O I：
10.1023/A:1022842203917
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Teicoplanin, a glucopeptide antibiotic, was produced by a mutant of Actinoplanes teicomyceticus at 300 mg l(-1) using mannose and yeast extract as carbon and nitrogen sources in flask culture and at 500 mg l(-1) in 5-1 jar fermenter. Teicoplanin production was 25-fold higher than in the parent strain.
引用
收藏
页码：537 / 540
页数：4
相关论文
共 50 条
  • [1] Production of teicoplanin by a mutant of Actinoplanes teicomyceticus
    Jae-Chan Lee
    Hae-Ryong Park
    Dong-Jin Park
    Kwang Hee Son
    Ki-Hong Yoon
    Young-Bae Kim
    Chang-Jin Kim
    Biotechnology Letters, 2003, 25 : 537 - 540
  • [2] Production of teicoplanin by valine analogue-resistant mutant strains of Actinoplanes teichomyceticus
    Jin Z.
    Wang M.
    Cen P.
    Applied Microbiology and Biotechnology, 2002, 58 (1) : 63 - 66
  • [3] Large-scale fermentation for the production of teicoplanin from a mutant of Actinoplanes teichomyceticus
    Lee, JC
    Min, JW
    Park, DJ
    Son, KH
    Yoon, KH
    Park, HR
    Parks, YS
    Kwon, MG
    Lee, JM
    Kim, CJ
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2005, 15 (04) : 787 - 791
  • [4] Production of teicoplanin by valine analogue-resistant mutant strains of Actinoplanes teichomyceticus
    Jin, ZH
    Wang, MR
    Cen, PL
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2002, 58 (01) : 63 - 66
  • [5] Production of teicoplanin by Actinoplanes teichomyceticus in continuous fermentation
    Vara, AG
    Hochkoepple, A
    Nielsen, J
    Villadsen, J
    BIOTECHNOLOGY AND BIOENGINEERING, 2002, 77 (05) : 589 - 598
  • [6] Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus
    Lilia Horbal
    Nestor Zaburannyy
    Bohdan Ostash
    Sergiy Shulga
    Victor Fedorenko
    World Journal of Microbiology and Biotechnology, 2012, 28 : 2095 - 2100
  • [7] Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus
    Horbal, Lilia
    Zaburannyy, Nestor
    Ostash, Bohdan
    Shulga, Sergiy
    Fedorenko, Victor
    WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2012, 28 (05): : 2095 - 2100
  • [8] Growth and production kinetics of a teicoplanin producing strain of Actinoplanes teichomyceticus
    Heydorn, A
    Suhr-Jessen, T
    Nielsen, J
    JOURNAL OF ANTIBIOTICS, 1999, 52 (01): : 40 - 44
  • [9] Teicoplanin biosynthesis genes in Actinoplanes teichomyceticus
    Sosio, M
    Bianchi, A
    Bossi, E
    Donadio, S
    ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 2000, 78 (3-4): : 379 - 384
  • [10] Teicoplanin biosynthesis genes in Actinoplanes teichomyceticus
    Margherita Sosio
    Alessandra Bianchi
    Elena Bossi
    Stefano Donadio
    Antonie van Leeuwenhoek, 2000, 78 : 379 - 384
12345