Plasmodium vivax:: Genetic diversity of the apical membrane antigen-1 (AMA-1) in isolates from India

被引：33

作者：

Rajesh, Vidya

Elamaran, M.

Vidya, S.

Gowrishankar, M.

Kochar, Dhanpat

Das, Ashis ^{[1
]}

机构：

[1] Birla Inst Technol & Sci, Dept Biol Sci, Pilani 333031, Rajasthan, India

[2] SP Med Coll, Bikaner, India

来源：

EXPERIMENTAL PARASITOLOGY | 2007年 / 116卷 / 03期

关键词：

AMA-1; Plasmodium vivax; genetic diversity; polymorphism; India;

D O I：

10.1016/j.exppara.2007.01.006

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Malaria parasites exhibit sequence diversity for a number of stage specific antigens. Several studies have proved that apical membrane antigen-1 (AMA-1) is an effective target for eliciting a protective immune response in humans and other experimental animals. We have investigated the sequence variation in Plasmodium vivax AMA-1 (Pv AMA-1) from different Indian isolates. This is the first study of its kind for the nearly full length Pv AMA-1 from India. Our analysis reveals greater degree of genetic diversity in Pv AMA-1 than reported so far and identifies five novel haplotypes. This is significant to establish the antigenic repertoire of isolates in a malaria endemic country like India. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：252 / 256

页数：5

共 50 条

[21] Genetic diversity of the full length apical membrane antigen-1 of Plasmodium knowlesi clinical isolates from Peninsular Malaysia
Ng, Y. L.
Fong, M. Y.
Lau, Y. L.
TROPICAL BIOMEDICINE, 2021, 38 (02) : 159 - 164
[22] Analysis of the Plasmodium vivax apical membrane antigen-1 gene from re-emerging Korean isolates
Joon-Yong Chung
Eui-Hyun Chun
Jin-Ho Chun
Weon-Gyu Kho
Parasitology Research, 2003, 90 : 325 - 329
[23] Genetic diversity and selection at the Plasmodium vivax apical membrane antigen-1 (PvAMA-1) locus in a Sri Lankan population
Gunasekera, Anusha M.
Wickramarachchi, Thilan
Neafsey, Daniel E.
Ganguli, Ishani
Perera, Lakshman
Premaratne, Prasad H.
Hartl, Daniel
Handunnetti, Shiroma M.
Udagama-Randeniya, Preethi V.
Wirth, Dyann F.
MOLECULAR BIOLOGY AND EVOLUTION, 2007, 24 (04) : 939 - 947
[24] Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P-falciparum AMA-1, and antibody-mediated inhibition of red cell invasion
Kocken, CHM
Narum, DL
Massougbodji, A
Ayivi, B
Dubbeld, MA
van der Wel, A
Conway, DJ
Sanni, A
Thomas, AW
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 109 (02) : 147 - 156
[25] STRUCTURE OF THE APICAL MEMBRANE ANTIGEN-I (AMA-1) OF PLASMODIUM-CHABOUDI
MARSHALL, VM
PETERSON, MG
LEW, AM
KEMP, DJ
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 37 (02) : 281 - 283
[26] The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels
Donahue, CG
Carruthers, VB
Gilk, SD
Ward, GE
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 111 (01) : 15 - 30
[27] A Plasmodium falciparum epical membrane antigen-1 (AMA-1) gene apparently generated by intragenic recombination
Eisen, DP
Marshall, VM
Billman-Jacobe, H
Coppel, RL
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1999, 100 (02) : 243 - 246
[28] Genetic Polymorphism and Natural Selection of Apical Membrane Antigen-1 in Plasmodium falciparum Isolates from Vietnam
Kang, Jung-Mi
Le, Huong Giang
Vo, Tuan Cuong
Naw, Haung
Yoo, Won Gi
Sohn, Woon-Mok
Trinh, Nguyen Thi Minh
Quang, Huynh-Hong
Na, Byoung-Kuk
GENES, 2021, 12 (12)
[29] Synthetic peptides from Plasmodium falciparum apical membrane antigen 1 (AMA-1) specifically interacting with human hepatocytes
Valbuena, J.
Rodriguez, L.
Vera, R.
Puentes, A.
Curtidor, H.
Cortes, J.
Rosas, J.
Patarroyo, M. E.
BIOCHIMIE, 2006, 88 (10) : 1447 - 1455
[30] Polymorphism in the gene encoding the apical membrane antigen-1 (AMA-1) of Plasmodium falciparum.: X.: Asembo Bay Cohort Project
Escalante, AA
Grebert, HM
Chaiyaroj, SC
Magris, M
Biswas, S
Nahlen, BL
Lal, AA
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 113 (02) : 279 - 287

← 1 2 3 4 5 →