Alkynylsilanes as convenient precursors for the stereoselective synthesis of (E)-disubstituted alkenes

被引：0

作者：

Zhao, H ^{[1
]}

Cai, MZ ^{[1
]}

机构：

[1] Jiangxi Normal Univ, Dept Chem, Nanchang 330027, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2002年 / 12期

关键词：

hydromagnesiation; (E)-disubstituted alkene; stereoselective synthesis;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hydromagneisation of alkynylsilanes 1 gives (Z)-alpha-silylvinyl Grignard reagents 2, which are reacted with alkyl iodides or aryl iodides in the presence of Cul or Pd(PPh3)(4) catalysts to afford (Z)-1,2-disubstituted vinylsilanes 3 in good yields. Intermediates 3 can undergo a desilylation reaction to give (E)-disubstituted alkenes 4 in high yields.

引用

页码：608 / 610

页数：3

共 50 条

[1] (E)-α-Bromovinylselenides as Convenient Precursors for Stereoselective Synthesis of Trisubstituted Alkenes
蔡明中
黄佳娣
郝文燕
ChineseJournalofChemistry, 2003, (11) : 1491 - 1493
[2] (E)-α-bromovinylselenides as convenient precursors for stereoselective synthesis of trisubstituted alkenes
Cai, MZ
Huang, JD
Hao, WY
CHINESE JOURNAL OF CHEMISTRY, 2003, 21 (11) : 1491 - 1493
[3] (E)-α-iodovinylstannanes as convenient precursors for stereoselective synthesis of trisubstituted alkenes
Cai, MZ
Ye, HD
Zhao, H
Song, CS
JOURNAL OF CHEMICAL RESEARCH-S, 2003, (08): : 465 - 467
[4] (E)-a-Selanylvinylstannanes as Convenient Precursors for Stereoselective Synthesis of Trisubstitnted Alkenes
Synthesis, 4 (417):
[5] (E)-alpha-selanylvinylstannanes as convenient precursors for stereoselective synthesis of trisubstituted alkenes
Huang, X
Ma, Y
SYNTHESIS-STUTTGART, 1997, (04): : 417 - &
[6] (Z)-α-Selanyl alkenyl Grignard reagents as convenient precursors for stereoselective synthesis of trisubstituted alkenes
Cai, MZ
Peng, CY
Huang, JD
CHINESE CHEMICAL LETTERS, 2002, 13 (12) : 1164 - 1167
[7] Stereoselective synthesis of (E)-α-halovinylsilanes via hydrozirconation of alkynylsilanes
Cai, MZ
Huang, JD
Ye, XL
Song, CS
JOURNAL OF CHEMICAL RESEARCH-S, 2003, (12): : 770 - 771
[8] (Z)-a-Selanyl Alkenyl Grignard Reagents as Convenient Precursors for Stereoselective Synthesis of Trisubstituted Alkenes
Ming Zhong CAI*
Chinese Chemical Letters, 2002, (12) : 1164 - 1167
[9] A stereoselective synthesis of (E)-allylic alcohols via the hydromagnesiation of alkynylsilanes
Cai, MZ
Peng, CY
Zhao, H
Hao, WY
JOURNAL OF CHEMICAL RESEARCH-S, 2003, (05): : 296 - 298
[10] Stereoselective synthesis of (E)-α-selenenylvinylsilanes via the hydromagnesiation reaction of alkynylsilanes
Zhao, H
Cai, MZ
SYNTHESIS-STUTTGART, 2002, (10): : 1347 - 1350

← 1 2 3 4 5 →