Synthesis of (S)-(+)-α-methoxymethyldihydro-coumarin:: Absolute configuration of the reduced product in enantioselective radical-mediated reduction

被引：0

作者：

Murakata, M ^{[1
]}

Tsutsui, H ^{[1
]}

Hoshino, O ^{[1
]}

机构：

[1] Sci Univ Tokyo, Fac Pharmaceut Sci, Shinjuku Ku, Tokyo 162, Japan

来源：

HETEROCYCLES | 1997年 / 46卷

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(S)-(+)-alpha-Methoxymethyldihydrocoumarin was synthesized starting from (R)-2-benzyl-3-hydroxypropyl acetate. Consequently, the absolute configuration of the reduced product obtained by radical-mediated reduction of alpha-iodo-alpha-methoxymethyldihydrocoumarin was determined to be R.

引用

页码：517 / 522

页数：6

共 34 条

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[34] An efficient method for the synthesis of enantiopure 2,3-anti-propionate aldols involving a 3,5-syn- or anti-diol subunit through chiral borane-mediated enantioselective aldol reaction coupled with radical reduction
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