Ultrasensitive and ratiometric two-photon fluorescence imaging of Golgi polarity during drug-induced acute kidney injury

被引：29

作者：

Wang, Hui ^{[1
]}

Dong, Mingyan ^{[1
]}

Wang, Hongtong ^{[1
]}

Huang, Fang ^{[1
]}

Li, Ping ^{[1
]}

Zhang, Wei ^{[1
]}

Zhang, Wen ^{[1
]}

Tang, Bo ^{[1
]}

机构：

[1] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Coll Chem Chem Engn & Mat Sci, Minist Educ,Inst Biomed Sci,Key Lab Mol & Nano Pr, Jinan 250014, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 47期

基金：

中国国家自然科学基金;

关键词：

LIVING CELLS; STRESS; PH;

D O I：

10.1039/d1cc01411k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We synthesized an ultrasensitive probe TP-Golgi for the two-photon ratiometric fluorescence imaging of Golgi polarity. Probe TP-Golgi possesses a large Stokes shift, excellent sensitivity and good selectivity to quantitatively detect environmental polarity. By application of TP-Golgi, we found that the Golgi polarity increased obviously in the kidneys of mice with AKI.

引用

页码：5838 / 5841

页数：4

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